Rezultaty - "King's College London"

Aims: Medical professionals are highly likely to come into contact with individuals who experience gambling harm during their careers. Around 5.5% of women and 11.9% of men globally experience some degree of gambling harm, and they are 15 times more likely to die by suicide than the general populati...

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More than one third of candidates for bariatric surgery suffer with clinical depression. Significant reduction in depression following bariatric surgery has been shown, but this is not consistent for all patients. The biological mechanisms behind the association between obesity and depression and be...

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ABSTRACT Introduction Some people experience persistent symptoms, such as fatigue, brain fog and breathlessness, long after the onset of COVID‐19 infection. This is known as the post‐COVID syndrome (PCS). We developed a unique and holistic psycho‐physiological intervention that integrates Acceptance...

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ABSTRACT: Background: To develop a 3D motion-corrected simultaneous multislice-balanced steady state free precession (SMS)-bSSFP acquisition to enable free-breathing myocardial perfusion with high spatial resolution and coverage. Methods: A fast diaphragmatic respiratory navigator (fastNAV) module...

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Cytoplasmic mislocalisation and nuclear depletion of TDP-43 are pathological hallmarks of amyotrophic lateral sclerosis (ALS), including mutations in the C9ORF72 gene that characterise the most common genetic form of ALS (C9ALS). Studies in human cells and animal models have associated cytoplasmic m...

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ABSTRACT Inhalation of biopersistent nanoplastics may have adverse effects on lung health. By varying the acetate content of poly(vinyl acetate‐co‐alcohol) (PVAc), model nanoplastics with different surface hydrophobicity can be produced to study the effects of nanoplastic hydrophobicity in the lung....

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Summary: In this review, we explore the application of regulatory T cells (Tregs) as cellular therapies in the setting of autoimmune liver diseases and liver transplantation. At present, there are limited treatment options for end-stage liver disease, which in many cases requires transplantation. Fo...

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The potential of autonomous robots to assist humans in emergency situations remains a prominent area of innovation. However, such developments may present profound societal and ethical challenges. Ideally, an active integration of Responsible Research and Innovation (RRI) allows for harnessing innov...

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Abstract Objective To investigate the patient, treatment and oncological prognostic factors for multiple mental well‐being outcomes in prostate cancer. Patient and Methods The MIND‐P study was a multi‐institutional prospective cohort study recruiting newly diagnosed prostate cancer patients for 12 m...

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Background: Health literacy (HL) has been deemed central to preventing and controlling non-communicable diseases by the WHO. The association between HL, other social determinants of health and outcomes in people with inflammatory arthritis (IA) remains poorly understood.We aimed to determine the ass...

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ABSTRACT Background Chronic back pain (CBP) is a major cause of disability globally. While its etiology is multifactorial, specific contributing genetic and environmental factors remain to be discovered. Paraspinal muscle fat has been shown in human and preclinical studies to be related to CBP. One...

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The pancreas has vital endocrine and exocrine functions that can be affected by life-threatening diseases such as diabetes and pancreatic cancer. Although animal models are essential for understanding pancreatic development and disease, they are limited by their low throughput and major species-spec...

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ABSTRACT Background Despite advance care planning (ACP) being associated with positive outcomes for residents in long‐term care facilities (LTCFs), the causal pathways between ACP and these outcomes are context‐specific and less understood. This lack of clarity can hinder the cultural adaptation and...

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Introduction: Dental anxiety is the apprehension experienced by an individual when confronted with matters related to dentistry, it impacts individuals' dental experiences and the dental healthcare providers’ professional lives, contributing to increased tension and potentially compromising per...

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Introduction: Emerging evidence suggests a relationship between chronic, intermittent, occluded exposure of a susceptible epithelium to urine and male genital lichen sclerosus (MGLSc), although human papillomavirus (HPV) may also play a role. Aims and methods: This study investigated the association...

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