Zoekresultaten - "Jiangsu"

Abstract Pancreatic cancer (PC) is an extremely deadly type of cancer, and the 5‐year survival rate remains less than 10%. The tumour microenvironment (TME) affects the occurrence, progression and treatment outcomes of PC. MicroRNAs (miRNAs) are essential to regulate PC TME. This review delves into...

Volledige beschrijving

ABSTRACT Background Gastric cancer (GC) remains a prevalent and lethal malignancy worldwide, underscoring the urgent need to identify novel therapeutic targets and elucidate the tumor microenvironment (TME) to enhance clinical outcomes. Methods IL36RN mRNA expression in GC tissues was analyzed using...

Volledige beschrijving

The substantial rise in health insurance expenditures, combined with delayed feedback on overspending from administrative departments, highlights the urgent need for timely reporting of such data. This study analyzed a large cohort of 549,910 discharged patients' medical records from the Wuxi H...

Volledige beschrijving

Abstract Organic UV photodetectors using a transistor architecture can yield higher photoresponsivity than diode‐based devices because of the presence of a gate electrode. However, a long‐term issue of these phototransistor devices is the slow response speed, which hinders their practical applicatio...

Volledige beschrijving

Saliva has already proven to be a prospective diagnostic bioresource for both early disease detection and timely intervention due to its easy accessibility, noninvasiveness, and reproducibility. However, the in-depth identification of salivary proteins needs to be further improved. Until now, only 3...

Volledige beschrijving

Kawasaki disease (KD) is a systemic immune vasculitis characterized by fever and is a common cause of acquired heart disease in children. The etiology of KD remains unclear, but it is generally believed to be an amplified inflammatory cascade caused by the combined action of infection and genetic su...

Volledige beschrijving

This study investigated the isoforms of porcine-origin Ral guanine nucleotide dissociation stimulator (RalGDS) in LLC-PK1 cells using reverse transcription-polymerase chain reaction (RT-PCR) and sequencing. Through segmented amplification, sequence assembly, and comparative genomics analysis, seven...

Volledige beschrijving

Mitochondria are essential for generating cellular energy and are significant in the pathogenesis of obesity. Human visceral and subcutaneous preadipocytes (HPA-v and HPA-s) were cultured into mature adipocytes. Intracellular triglyceride (TG) content was assessed using oil-red O staining and tissue...

Volledige beschrijving

Background & Aims: Metabolically unhealthy obesity (MUO) is characterized by hepatic steatosis and type 2 diabetes (T2D), distinct from metabolically healthy obesity (MHO). This study aimed to identify the key regulator responsible for MUO. Methods: Metabolomics analysis was conducted to com...

Volledige beschrijving

The backfilling process of initial gangue throwing followed by grouting with backfilling slurry solved the long-standing engineering problem of insufficient slurry transport distance. However, it resulted in the formation of a backfill body with a special layered structure in the goaf. Research on t...

Volledige beschrijving

Excessive or insufficient application of fertilizer has raised broader concerns regarding soil and environmental degradation. One-time application of slow release fertilizer (SF) has been widely used to reduce yield gap with potential maize yield and improve nitrogen use efficiency (NUE). A 2-year f...

Volledige beschrijving

Biaxial rotary tillage in dryland (DBRT) can complete biaxial rotary tillage with straw incorporation, secondary suppression, and ditching, and it has been previously studied in direct-seeded rice and wheat. However, the effects of DBRT on the mechanically transplanted rice yield and greenhouse gas...

Volledige beschrijving

Abstract The detrimental Fe element in Al‐Si cast alloy can be effectively removed by Fe‐containing intermetallics separation. However, the formation temperature of Fe‐containing intermetallics can be further improved to increase the removal efficiency of Fe element. The effects of the Cr/Mn atomic...

Volledige beschrijving

Objective(s): To assess the effect of catalpol, the major bioactive constituents of Rehmannia glutinosa, on our Alzheimer’s disease (AD) in vitro model.Materials and Methods: We employed the immortalized lymphocytes (lymphoblastoid cell line, LCL) from late-onset AD patients and co-cultured “them” t...

Volledige beschrijving

This paper systematically investigated the influence of sintering atmospheres, vacuum, and oxygen, on the microstructure and optical properties of Y₂O₃ ceramics. Compared with vacuum sintering, sintering in flowing oxygen atmosphere can effectively inhib...

Volledige beschrijving

Trichoderma is an important and widely used plant growth-promoting fungus (PGPF). In this study, stevia residue amended with amino acids hydrolyzed from animal carcasses was used for the production of Trichoderma guizhouense NJAU 4742 by solid-state fermentation, and then its potential to promote co...

Volledige beschrijving

Background: The isolation and culture of Mycoplasma pneumoniae (MP) is time-consuming and has a low success rate. On the basis of the fact that cell lines are susceptible to MP contamination, we explored the possibility of using Hep-2 cell culture for the isolation and culture of MP, to overcome thi...

Volledige beschrijving

Objective: The aim of this study was to analyse the long-term functional, subjective, and psychological results after single-digit replantation. Methods: Thirty cases of digital replantation (14 thumbs, 12 index fingers, 2 middle fingers, 1 ring finger, and 1 little finger) in 30 patients (7 females...

Volledige beschrijving

Background Brain frailty is characterized by imaging biomarkers of chronic cerebrovascular injury. Whether brain frailty improves the prediction of acute ischemic stroke complications and prognosis requires further study. Methods This multicenter, retrospective study included patients with acute isc...

Volledige beschrijving