खोज परिणाम - "Institute of Psychiatry"

Cytoplasmic mislocalisation and nuclear depletion of TDP-43 are pathological hallmarks of amyotrophic lateral sclerosis (ALS), including mutations in the C9ORF72 gene that characterise the most common genetic form of ALS (C9ALS). Studies in human cells and animal models have associated cytoplasmic m...

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More than one third of candidates for bariatric surgery suffer with clinical depression. Significant reduction in depression following bariatric surgery has been shown, but this is not consistent for all patients. The biological mechanisms behind the association between obesity and depression and be...

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IntroductionRecovery Colleges (RCs) exist in 28 countries and across five continents. The concept of recovery and recovery-oriented care has become widespread internationally and embedded in policy documentation and mental health services. As a result, Recovery Colleges, which focus on adult learnin...

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Aims: People with severe mental illnesses experience poorer physical health outcomes compared with the general population, partially related to fragmented care. The Integrating our Mental and Physical Healthcare Systems project implemented an Advice and Guidance Line, supported by colleagues in King...

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Aims: Recent research has focused on the inflammatory cascade as a key culprit in the aetiology of Bipolar disorder. We hypothesized that celecoxib, via its anti-inflammatory properties, may have a therapeutic role in mood disorder. The present study was a 4 weeks, open label case-control trial of c...

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<b>Aims</b>: Cue exposure therapy (CET) is a promising treatment approach for cocaine substance use disorder (SUD). CET specifically targets the psychological and physiological responses elicited by drug-related cues, aiming to reduce their motivational impact. To advance understanding o...

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ABSTRACT Introduction Some people experience persistent symptoms, such as fatigue, brain fog and breathlessness, long after the onset of COVID‐19 infection. This is known as the post‐COVID syndrome (PCS). We developed a unique and holistic psycho‐physiological intervention that integrates Acceptance...

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The number of identified neurodivergent individuals in UK higher education, within both student and staff populations, is steadily increasing, yet there is limited evidence on how best to support them. In the context of financial pressures and sector-wide transformation, setting priorities for neuro...

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Recently, the issues of violations of gender identity are becoming more relevant and discussed, the number of patients with a request for a sex change is increasing. The complexity of this issue requires clinicians to be competent in helping transgender people, as they sometimes face many obstacles...

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Background. Sexual disharmony is a significant factor in the destabilization of family relations, having a negative impact on the demographic situation. Disorders of sexual function often have comorbid associations with various somatic and mental illnesses, which determines the need for a comprehens...

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BackgroundThere is a rapidly growing evidence base for the effectiveness of creative health interventions in improving mental health, but few studies have explored implementation and scaling of these interventions. The aim of this study was to evaluate the perceived acceptability, appropriateness, a...

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ObjectiveThe purpose of the present study was to determine the prevalence of self-medication among psychiatric residents with self-reported mental disorders, and to study the factors associated with self-medication.MethodsA cross-sectional retrospective study was conducted with psychiatry residents...

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Background: Depression is a leading neuropsychiatric disorder causing disability worldwide. In recent years, biofeedback has been increasingly applied in the clinical treatment of depression. This study aims to explore the emerging trends and knowledge structure in biofeedback for depression. Method...

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In the 1950s, monoamine oxidase inhibitors transformed the pharmacological treatment of mental disorders as the first class of antidepressant drugs. Currently considered third-line medications for treatment-resistant depression, they are markedly underutilized. Despite the benefits of these drugs, c...

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Aims: Negative symptoms of schizophrenia are disabling and often show inadequate response to antipsychotic treatment. Dysfunction in cortical regions such as the anterior cingulate cortex (ACC) and medial prefrontal cortex (mPFC) has been implicated in these symptoms. While repetitive transcranial m...

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The article presents the results of screening data from a simultaneous study of 443 outpatient cards of patients with schizophrenic spectrum disorders who were under dynamic outpatient monitoring in two areas of the psycho-neurological dispensary No. 2 in Moscow in order to assess the incidence of t...

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Background Recovery colleges (RCs) support personal recovery through education, skill development and social support for people with mental health problems, carers and staff. Guided by co-production and adult learning principles, RCs represent a recent mental health innovation. Since the first RC op...

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The aim of the study was to study the clinical and typological features of eating disorders in patients with schizophrenia spectrum disorders.Materials and methods. We studied 136 patients (84 women and 52 men) with schizophrenia spectrum disorders, aged 19 to 58 years, mean age 37.6±9.8 years; the...

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Many people experiencing mental ill health are trapped in cycles of worsening social exclusion. Individual Placement and Support (IPS) is being implemented to support those with mental ill health into employment. However, this intervention does not address the many challenges faced by those who are...

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