Search Results - "IGF2BP3"

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  1. 1
    IGF2BP3 Modulates mRNA Splicing and Stability to Promote Trophoblast Progression via Interaction with PDE3A and Suppression by miR-196a-5p in Preeclampsia

    IGF2BP3 Modulates mRNA Splicing and Stability to Promote Trophoblast Progression via Interaction with PDE3A and Suppression by miR-196a-5p in Preeclampsia by Chunyan Li, Pingpo Ming, Cuifang Fan, Jiao Chen, Jing Yang

    Published 2025-05-01

    <b>Background:</b> Preeclampsia (PE) is a pregnancy-specific disorder and a leading cause of maternal and fetal morbidity and mortality. Impaired trophoblast invasion is a hallmark of PE, and alternative splicing (AS) is crucial for trophoblast differentiation and placental development....

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    Expression of Insulin-like growth factor 2 mRNA-binding protein 3 and its diagnostic value in breast cancer

    Expression of Insulin-like growth factor 2 mRNA-binding protein 3 and its diagnostic value in breast cancer by Chao-Qun Wang, Jun-Kang Shao, Yan Wang, Shi-Ping Lu, Li-Jing Jiang, Zhi-Qun Du, Bi-Fei Huang

    Published 2025-07-01

    There is currently no established systematic explanation of the clinical application and diagnostic value of insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) in breast cancer. This study utilized immunohistochemistry (IHC) to assess the expression of the IGF2BP3 protein in 299 cases of...

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