Rezultaty - "Harvard T.H. Chan School of Public Health"

Background: Exposure to green space is associated with children’s mental health, but its impact on neurodevelopment has been underexplored, especially in socioeconomically disadvantaged populations. This study examined the link between exposure to green space before, during, and after pregnancy and...

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Background: Evidence on the association between maternal phenol exposure and inflammation during pregnancy is limited and inconsistent. Objective: To evaluate associations between urinary phenol biomarkers and serum inflammatory cytokines across pregnancy, and to examine whether associations vary by...

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Introduction: Community health centers and clinics are on the frontlines of climate change and adverse health effects, providing essential care to millions of low-income, uninsured, and underinsured populations across the country. The Climate Resilience for Frontline Clinics Toolkit (“the toolkit”)...

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Introduction Misinformation about cardiovascular health has the potential to negatively impact public health outcomes. Understanding the nature and spread of such misinformation is crucial for developing effective interventions to mitigate this potential risk. However, despite the critical importanc...

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Background Primary prevention of cardiovascular disease (CVD) focuses on treatment of risk factors, including hypercholesterolemia, hypertension, and type 2 diabetes mellitus. We investigated whether a healthy diet in adolescence prevents development of clinical risk factors or incidence of CVD in a...

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Abstract School system is a promising platform for addressing all forms of malnutrition in adolescents. However, little is known about the impact of integrated school health and nutrition programmes on adolescent nutrition and educational outcomes in low‐ and middle‐income countries (LMICs). This sy...

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The global rise in obesity prevalence and the incidence of early-onset cancer (diagnosed between 20 and 49 years of age) is a serious public health concern. We, therefore, evaluated the recent global trends in the incidence of early-onset obesity-related cancers and compared them to those of non-obe...

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Abstract Characterizing the timing of menarche and the factors that are associated with it is important for understanding a population's reproductive health needs and long‐term health trajectories. We estimated the age at the menstrual onset among adolescent girls and the association between di...

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Background: A novel ready-to-use microbiome-directed food (MDF) has been developed for the management of acute malnutrition using ingredients that promote repair of the gut microbiota of undernourished children. Objectives: This study aims to assess the acceptability of MDF compared with standard nu...

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Introduction Hypertensive disorders of pregnancy (HDP) have been linked with increased risk for maternal and offspring complications in high-income settings. However, in resource-limited settings, studies with robust measurement of HDP, including severity and timing, and perinatal outcomes are limit...

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Abstract Background MicroRNAs are small non-coding RNAs that regulate gene expression post-transcriptionally and show differential expression in various tissues with aging phenotypes. Detectable in circulation, extracellular microRNAs reflect (patho)physiological processes and hold promise as biomar...

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Abstract Anaemia among adolescents is a global health problem. However, evidence regarding its burden and risk factors, particularly for younger adolescents and in sub‐Saharan Africa (SSA), remains scarce. We aimed to assess the prevalence and potential determinants of anaemia among urban and semi‐u...

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Summary: Background: Since 1950, there have been increasingly atypical climatological patterns in the Amazon, some caused by El Niño-Southern Oscillation (ENSO) events (El Niño or La Niña). In 2023–2024, the region faced the most severe droughts in recorded history. These weather patterns are major...

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Abstract Adolescent diets may be influenced by the retail food environment around schools. However, international research to examine associations between the proximity of retail food outlets to schools and diet provides equivocal support for an association. This study aims to understand the school...

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Background: Solar and geomagnetic activity have been linked to a multitude of impacts on human health including cardiovascular disease (CVD), and total non-accidental mortality. However, this has not been assessed in the Eastern Mediterranean Region or the Middle East. Our study aimed to assess the...

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Gaussian processes (GPs) are sophisticated distributions to model functional data. Whilst theoretically appealing, they are computationally cumbersome except for small datasets. We implement two methods for scaling GP inference in Stan: First, a general sparse approximation using a directed acyclic...

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IntroductionPublic health leadership is a call to action, drawing us nearer to the individuals and communities burdened by health disparities and social injustice. Reimagining public health leadership to center health equity entails collective and community engaged applied practice, premised on humi...

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Background A lifestyle cardiovascular risk score (LCRS) and a genetic risk score (GRS) have been independently associated with myocardial infarction (MI) in Hispanics/Latinos. Interaction or joint association between these scores has not been examined. Thus, our aim was to assess interactive and joi...

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Abstract Mental health in adolescence is important for health and well‐being throughout the life course, but evidence from Sub‐Saharan Africa is sparse. This study aimed to assess the correlates of internalizing, externalizing and cumulative problems among early adolescents. This study used cross‐se...

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