Sökresultat - "Endometrial carcinoma"

The paper presents data on the clinical and morphological characteristics, clinical presentation, and treatment of clear cell carcinoma, as well as survival rates in patients with this condition. It shows an association of the expression of the intercellular adhesion molecules E-cadhedrin, α- and β-...

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Summary: Background: Endometrial cancer is the most common gynaecological cancer in high-income countries. In addition to environmental risk factors, genetic predisposition contributes towards endometrial cancer development but is still incompletely defined. Methods: Building on genome-wide associa...

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BackgroundEndometrial carcinoma (EC) is one of the most common gynecologic malignancies, with increasing global morbidity and mortality rates. Curcumol, a sesquiterpenoid hemicrystalline compound, exhibits notable pharmacological effects, including anticancer, anti-inflammatory, and antiviral proper...

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Central nervous system (CNS) involvement by endometrial carcinoma is uncommon. Among 1710 patients registered for brain metastases at our institution between 1990 and 2012, 3 (0.18 %) developed brain metastases. All lesions (1 multiple, 2 single) were contrast enhancing on com- puted tomography scan...

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The goal of study was to study the incidence and the clinical manifestation of the endometrial pathology in premenopausal period. 73 premenopausal women with various endometrial pathology were examined. The average age of the examined was 47.82 ± 0.27 (45-51) years. The age of the menarche was 11.0...

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Introduction: Endometrioid endometrial carcinoma (EEC) is the most common type of endometrial cancer, accounting for approximately 80-90% of all endometrial cancer cases. Endometrial hyperplasia deserves special attention because of its relationship with endometrialcinoma. This study's goal was...

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Endometrial cancer is one of the most common gynaecological cancers in both the United States and the Russian Federation, and the rate continues to rise. Although early-stage endometrial cancer is associated with a favourable 5-year survival rate (96%), this rate in patients with distant metastases...

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Abstract Endometrial carcinoma (EC) is the most common malignant tumor of the female genital tract in developed countries. The prognosis of early stage EC is favorable, but a subset faces high risk of cancer progression or recurrence. EC has a poor prognosis upon progression to advanced or metastati...

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Endometrial carcinoma (EC) represents one of the most prevalent malignancies within the female reproductive system. The frequency of its occurrence is on the rise annually, and patients diagnosed at advanced stages face a less favorable prognosis. Recent studies have highlighted the significant infl...

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IntroductionImmunogenic cell death (ICD) is the phenomenon in which tumor cells undergo the transition from a non-immunogenic state to an immunogenic state upon their demise as a result of external stimuli. While ICD systems have been widely adopted in oncological research, their specific utilizatio...

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The prognostic significance of the microcystic, elongated, and fragmented (MELF) invasion pattern in endometrial carcinoma (EC) has not been fully elucidated. This study conducted a systematic search across five electronic databases (PubMed, EMBASE, Cochrane, Web of Science, and the Chinese National...

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ObjectiveTo explore the expression of human epidermal growth factor receptor 2 (HER2) and its associations with clinical, pathological, and imaging characteristics in endometrial carcinoma (EC) patients. MethodsA retrospective analysis was conducted on 214 patients with newly diagnosed EC treated at...

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BackgroundThe incidence and mortality of uterine corpus endometrial carcinoma (UCEC) is increasing. Despite advances in diagnosis and treatment, the fundamental molecular mechanisms remain unclear to some extent. In this study, the role and clinical significance of Cyclin D2 (CCND2) in UCEC is discu...

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Purpose of the study. The objective of the present study was to examine the levels of TGFβ1, EGF, and EGFR in the blood and tissue of morphologically distinct endometrial tumors, including uterine serous carcinoma (USC), clear cell endometrial cancer (CCEC), and G3 endometrioid adenocarcinoma (EAC)....

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High efficacy of anti-PD-1 therapy has been shown in malignant tumors with mismatch repair deficiency. According to the literature review, mismatch repair deficiency is determined in 20–40 % of all endometrial cancer cases and up to 48 % of its endometrioid subtype. We report the short review of the...

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The article presents the results of organ-preserving treatment protocol of atypical endometrial hyperplasia and well-differentiated endometrial carcinoma in young women. This protocol was applied in 24 patients. The period of patients observation was 3—6 years. During 6—9 months the patients were gi...

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Patients with LS-EC can be treated with progestin-based fertility-sparing treatment under close monitoring, and pregnancy is recommended as soon as possible after complete remission (CR) of the disease, with assisted reproduction, supplemented by PGT-M, to minimize the probability of inheritance of...

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