Search Results - "Antibacterial"
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The antimicrobial peptide Cec4 has therapeutic potential against clinical carbapenem-resistant Klebsiella pneumoniae
Published 2025-07-01Subjects: Get full textABSTRACT The rapid increase in carbapenem-resistant Klebsiella pneumoniae (CRKP) infections, along with the cross-resistance of CRKP to other antibiotics, has created an urgent need for novel therapeutic agents. Among the potential options for next-generation antibiotics, antimicrobial peptides (AMP...
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The study of antimicrobial and antifungal activity of Nʹ-ylidene-2(3-(adamantan-1-yl)-1H-1,2,4-triazole-5-yl)thioacetohydrazides
Published 2015-08-01Subjects: Get full textAim. The modern arsenal of antimicrobial drugs is characterized by high toxicity, moreover their widespread and uncontrolled use leads to the resistant strains’ selection. It creates favorable basis for the synthesis of new compounds with pronounced pharmacological activity. Methods and results....
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In Vitro Study of Antimicrobial Activity of Lactoferrins from Various Sources
Published 2020-05-01Subjects: Get full textComparative antimicrobial activity of lactoferrins from various sources (native lactoferrin from Laprot, human hololactoferrin, recombinant human lactoferrin isolated from the cultural medium of permissive cell culture transfected using pseudoadenovirus nanostructure with the human lactoferrin gene,...
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Synthesis, Characterization and Antimicrobial Activity Study of Some New Substituted Benzoxazole Derivatives
Published 2019-09-01Subjects: “…Antibacterial activity, Benzoxazole, Gram positive, 2-Mercaptobenzoxazole, Specific antibacterial drug.…”This research included the preparation of 2-mercaptobenzoxazole (N1) by the reaction of ortho-aminophenol with carbon disulfide in an alcoholic potassium hydroxide solution. The 2-mercapto benzoxazole (N1) was then treated with hydrazine to obtain the 2-hydrazino benzoxazole (N2). A number of hydraz...
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Antimicrobial Effects of Tannic Acid Combined with Plasma-Activated Water and Their Application in Strawberry Preservation
Published 2025-06-01Subjects: Get full textThis study investigated the combined antibacterial effects of PAW with natural antimicrobial agents and further examined the impact of this technology on postharvest strawberry preservation. The optimal PAW preparation condition was determined at 50 min at 400 W, although PAW alone showed limited ef...
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Diagnosis and antimicrobial therapy of infections caused by polyresistant microorganisms (updated 2024)
Published 2025-04-01Subjects: Get full textStrains of microorganisms characterized by resistance to antimicrobial drugs used in medical organizations continue to spread in most regions of the world, including Russia. This naturally affects both the effectiveness of antimicrobial therapy and the tactics of its use not only in adults but also...
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Guidelines of the Association of Anesthesiologists-Intensivists, the Interregional Non-Governmental Organization Alliance of Clinical Chemotherapists and Microbiologists, the Inter...
Published 2022-05-01Subjects: Get full textStrains of microorganisms characterized by resistance to antimicrobial drugs used in medical organizations continue to spread In most regions of the world including Russia. It is clear that it affects both the effectiveness of antimicrobial therapy and tactics and strategy of its use not only in adu...
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Search for New Types of Raw Materials for Antibacterial Drugs
Published 2020-05-01Subjects: Get full textAntibacterial properties of the mycelium culture of Fomitopsis officinalis (Vill.: Fr.) Bondartsev et Singer were investigated. It was shown to be an additional source for production of antibacterial substances active against gramnegative bacteria. In the future, the use of Fomitopsis officinalis fo...
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The importance of antibiotics and the evolution of resistance to antimicrobial substances
Published 2024-06-01Subjects: Get full textBy exploring the history of antibiotic discovery and how antimicrobial resistance has become a global problem, this study aims to provide a comprehensive perspective on the impact of these factors on public health. At the same time, we will analyze the strategies proposed to counter this worrying de...
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Comparison of Antibacterial Activities of Tobramycin Inhalation Solutions
Published 2020-05-01Subjects: Get full textAntibacterial spectra of Tobramycin-Gobby(solution for inhalation 60 mg/ml, «GobbyNovag C.A.», Argentina) and Toby (solution for inhalation 60 mg/ml, «Cardinal Health Inc.», USA) were estimated comparatively. The estimation involved 75 clinical isolates of microorganisms from the Culture Collection...
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Synthesis and Characterization of Some New Pyrazoline and Isoxazoline Derivatives as Antibacterial Agents
Published 2016-09-01Subjects: “…"Chalcones, Pyrazolines, Isoxazolines, Antibacterial"…”In this paper some chalcones (C1-C8) are prepared based on the reaction of one mole of substituted acetophenone with one mole of substituted benzaldehydes in the presence of (40%) sodium hydroxide as a base. Pyrazolines (P1–P8) are prepared from the reaction of chalcones (C1-C8) with hydrazine hydra...
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ANTIBACTERIAL THERAPY OF INFECTED PANCREATIC NECROSIS IN A MULTIFIELD SURGICAL HOSPITAL
Published 2012-07-01Subjects: Get full textThe work is based, on the analysis of the results of complex conservative and surgical treatment of 50 patients with infected, forms of pancreatic necrosis, who were treated in surgical wards of Republican, hospital № 2 — Center of Emergency Medical Care of Sakha Republic (Yakutia) during the period...
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Placenta peptides: antibacterial effects
Published 2024-01-01Subjects: Get full textMass spectrometric sequencing of peptides in Laennec indicated the presence of 5 peptides in the drug, the biological activity of which may determine the antibacterial properties of the drug. The most significant result of this study is the presence in Laennec of a fragment of the antibacterial pept...
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Analysis of The Antibiotic Resistance Problem
Published 2023-10-01Subjects: Get full textAntibiotic resistance is a global health problem. Its solution requires concerted efforts on the scale of global cooperation. Programs to prevent the development of antibiotic resistance, as well as to stimulate the development of new drugs with antimicrobial activity are implemented in a lot of cou...
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Antioxidant and Antibacterial Potency of Red Chillies Extract (Capsicum annum var. Longum)
Published 2022-03-01Subjects: “…antibacterial…”Chili (Capsicum annum var. Longum) is a horticultural plant that is widely used as raw material for the food and pharmaceutical industry. Generally, chili fruit contains phenolic chemical compounds of flavonoid and capcaisinoid compounds. Bioactive compounds in chili such as phenols, flavonoids and...
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PHARMACOEPIDEMIOLOGICAL AND PHARMACOECONOMIC ANALYSIS OF TREATMENT OF ENDOMETRIT IN-HOSPITAL
Published 2015-12-01Subjects: Get full textPharmacoepidemiological and pharmacoeconomical analysis of endometrit drug therapy at special treatment-and-prophylactic institutions of the city of Tomsk. Estimate the intensity of the appointment of antibacterial drugs endometrit therapy using the methodology of the WHO ATC/DDD, calculated indicat...
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Synthesis and In Vitro Antibacterial Studies of Two New Hydrazone Derivatives
Published 2024-11-01Subjects: Get full textThroughout history to the present day, infectious diseases have been a persistent global threat, causing significant harm to public health and economic stability. To address these challenges, the development of novel antimicrobial drugs is crucial. Hydrazones have gained significant attention in the...
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Effect of leaves Extracts of Duranta repens on growth and activity of some types of Pathogenic Bacteria and Some types of Fungi
Published 2009-03-01Subjects: “…"Duranta repens , antifungal , antibacterial"…”A study were conducted to examinate the effect of organic and aqueous (Hot, Cold) Extracts from leaves of Duranta repens on the growth and activities of the following types of Bacteria:- Staphylococcus aureus,Streptococcus pyogens ,Escherichia coli,Klebsilla pneumonia, in addition to the yeast Candi...
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Antibacterial activity of ginger extracts and its essential oil on some of pathogenic bacteria
Published 2010-09-01Subjects: “…"Antibacterial activity, ginger extracts"…”The antimicrobial activity of ginger extracts ( cold-water, hot-water, ethanolic and essential oil ) against some of pathogenic bacteria ( Escherichia coli , Salmonella sp , Klebsiella sp , Serratia marcescens, Vibrio cholerae , Staphylococcus aureus , Streptococcus sp) was investigated using Disc...
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Impact of Antibacterial Agents in Horticulture: Risks to Non-Target Organisms and Sustainable Alternatives
Published 2025-07-01Subjects: “…antibacterial agents…”The global population is rising at an alarming rate and is projected to reach 10 billion by 2050, necessitating a substantial increase in food production. However, the overuse of chemical pesticides, including antibacterial agents and synthetic fertilizers, poses a major threat to sustainable agricu...
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