Search Results - "Amino acid"
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Emerging Insights into the Relationship Between Amino Acid Metabolism and Diabetic Cardiomyopathy
Published 2025-06-01Subjects: “…amino acid metabolism…”Diabetes mellitus (DM) is a complex global pandemic that frequently leads to multiple complications. Diabetic cardiomyopathy (DCM) is the primary cause of heart failure in patients with type 1 and 2 diabetes and is fundamentally characterized by abnormalities in myocardial structure and function. Me...
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The Molecular Basis of Amino Acids Sensing
Published 2025-07-01Subjects: “…amino acid sensing…”Abstract Amino acids are organic compounds that serve as the building blocks of proteins and peptides. Additionally, they function as bioactive molecules that play important roles in metabolic regulation and signal transduction. The ability of cells to sense fluctuations in intracellular and extrace...
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Amino acids shape the metabolic and immunologic landscape in the tumor immune microenvironment: from molecular mechanisms to therapeutic strategies
Published 2025-07-01Subjects: Get full textThe tumor immune microenvironment (TIME) represents a complex battlefield where metabolic competition and immune evasion mechanisms converge to drive cancer progression. Amino acids, with their multifaceted biological roles, have emerged as pivotal regulators of tumor cell proliferation and immune c...
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Revisiting D‐Acylases for D‐Amino Acid Production
Published 2025-06-01Subjects: Get full textABSTRACT N‐Acyl‐D‐amino acid deacylases (EC 3.5.1.81, also known as D‐acylases) have been studied for decades for their utility in the kinetic resolution of N‐acetyl‐D,L‐amino acids (NAAs) due to a marked stereospecificity. In conjunction with an N‐succinyl‐amino acid racemase (NSAR), they impulse t...
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Metabolic Response of Pakchoi Leaves to Amino Acid Nitrogen
Published 2014-04-01Subjects: “…amino acid…”Different nitrogen (N) forms may cause changes in the metabolic profiles of plants. However, few studies have been conducted on the effects of amino acid-N on plant metabolic profiles. The main objective of this study was to identify primary metabolites associated with amino acid-N (Gly, Gln and Ala...
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Changes in the amino acid pool in the rat parietal lobe and hippocampus with incomplete cerebral ischemia
Published 2023-12-01Subjects: “…amino acid…”Introduction. Amino acids and their derivatives are involved in synaptic transmission as neurotransmitters and neuromodulators, and some of them are involved in the formation of neurotransmitters of the nervous system. Therefore, the study of the state of the amino acid pool in incomplete cerebral i...
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CHEMICAL COMPOSITION AND AMINO ACID PROFILE OF FRESH AND STEAMED COBIA (Rachycentron canadum L.)
Published 2020-07-01Subjects: “…amino acid, cobia, essential, nonessential, steaming…”<p>Cobia (<em>Rachycentron canadum</em>) is economically important fish with good prospects because of fast growing and easily cultured. Cobia is usually processed by many methods including steaming. The purposes of this research were to determine the effect of steaming process on...
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ELECTROCHEMICAL INFLUENCE OF AMINO ACIDS ON THE CORROSION OF BIOALLOYS
Published 2024-12-01Subjects: Get full textShape memory alloys are of great commercial importance from biomedical applications to smart materials. The electrochemical behavior of Cu-Al-Zn alloy in phosphate buffer without and in the presence of amino acid was investigated. Electrochemical researches were performed in a traditional three-elec...
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From Logs to Bags: A Metabolic Blueprint of Sanghuang Cultivation Revealed by UPLC-Q-TOF-MS/MS and Amino Acid Profiling
Published 2025-07-01Subjects: Get full textSanghuang (SH), a natural fungal resource used for food and medicinal purposes, has drawn considerable attention due to its pharmacological effects and efficacy. This study focused on Wild Sanghuang (WS) and Sanghuang cultivated using two different methods: Duanmu Sanghuang and Mycelium Sanghuang. U...
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Phenylalanine modulates casein synthesis in bovine mammary epithelial cells by influencing amino acid transport and protein synthesis pathways
Published 2025-07-01Subjects: Get full textThe efficiency of phenylalanine (Phe) utilization for milk protein synthesis in dairy cows is limited, and its uptake and metabolic mechanisms in the mammary tissue remaining unclear. This study investigated the effects of Phe availability (0.07, 0.14, 0.28, and 0.56 mM) on amino acid metabolism and...
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Structural information of trypsin isozyme GT-B from grass carp (Ctenopharyngodon idellus) intestines
Published 2008-05-01Subjects: Get full textIn order to learn the correlation between chemical composition, structure and properties of grass carp intestine trypsin isozyme GT-B, the composition of amino acids, characteristic of ultraviolet absorption, and secondary structural units of this enzyme were investigated by instrumental and chemica...
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A Study of the thermodynamic parameters (functions) of complexes formation of Sulfanilamid with metal ions and DL-Alanine by potentiometric method
Published 2019-05-01Subjects: Get full textThe current study deals with the preparation of disulfonalmide complexes composed of the sulfanilamid drug , the salt of chromium(III) and the trisulfonalmide complexes composed of the sulfonalmide drug , the metal salt and the amino acid (alanin), as well as study in the stability constant of ea...
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Blood serum amino acid pool violation of in patients with liver cirrhosis
Published 2021-03-01Subjects: “…liver cirrhosis; amino acid pool; intestinal dysbiosis.…”Objective. To investigate serum amino acid pool changes in patients with liver cirrhosis. Materials and methods. 95 patients with liver cirrhosis were participated in the study. In the 1st group (class A disease severity according to Child- Pugh score) there were 18 (18.95%) patients, in the 2nd ...
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Asparagine Synthetase Gene <i>OsASN2</i> Is Crucial for Rice Seed Development and Germination
Published 2025-06-01Subjects: Get full textSeed development plays a critical role in determining both crop yield and grain quality in rice. As a key nutrient storage organ, the rice endosperm development not only contributes to grain filling but also plays an essential role during the early stages of seed germination. Amino acid metabolism i...
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Quality variation of house cricket (Acheta domesticus) powder from Thai farms: Chemical composition, micronutrients, bioactive compounds, and microbiological safety
Published 2025-07-01Subjects: Get full textThis study assessed the quality of house cricket (Acheta domesticus) powders sourced from three farms in Thailand, focusing on composition, bioactive compounds, and microbiological safety. The powders contained high protein (59–60 g/100 g DW), lipids (19–20 g/100 g DW), and essential amino acid inde...
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Heating Experiments on Benthic Foraminifera Ammonia sp. to Assess the Suitability of Amino Acid-Based Dating
Published 2024-09-01Subjects: “…amino acid racemization…”Sub-milligram fossil biominerals, mainly benthic foraminifera, have been recently used to estimate the age of sediments determined from amino acid dating due to the minimum sample size requirement for reverse-phase high-performance liquid chromatography (RP-HPLC). This includes the collection of Amm...
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Progress of research on microbiological chitosanases
Published 2004-03-01Subjects: Get full textChitosan is one of the most abundant polysaccharides in nature. It consists of β-1, 4-linked D-glucosamine (GlcN) and N-acetyl-β-Dglucosamine (GlcNAc) residues. Chitosanases catalyze the hydrolytic breaking of its glucosidic bond and produce chitosan, which are widely applied for various purposes in...
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Effect of graded levels of fiber from alfalfa meal on apparent and standardized ileal digestibility of amino acids of growing pigs
Published 2015-12-01Subjects: Get full textTwo experiments were conducted to determine the effects of fiber level from alfalfa meal and sampling time on the apparent ileal digestibility (AID) and standardized ileal digestibility (SID) of amino acids (AA) in growing pigs. A total of 24 ileal-cannulated pigs (Duroc×(Large White×Landrace) with...
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Observation on changes of trace elements and amino acids in serum of patients with hepatocellular carcinoma
Published 2025-03-01Subjects: “…|hepatocellular carcinoma(hcc)|trace element|amino acid…”Objective To explore the changes in trace elements and amino acid profiles in serum of patients with hepatocellular carcinoma(HCC) providing a reference for clinical diagnosis and treatment.Methods A total of 104 patients with HCC who underwent surgical treatment in the Department of Hepatobiliary...
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Role of amino acids in the regulation of hepatic gluconeogenesis and lipogenesis in metabolic dysfunction-associated steatotic liver disease
Published 2025-07-01Subjects: Get full textMetabolic dysfunction-associated steatotic liver disease (MASLD) and its relatively advanced form, metabolic dysfunction-associated steatohepatitis (MASH), are becoming increasingly prevalent worldwide, making their prevention and management an urgent global health priority. Central to their develop...
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