Search Results - "Amino acid"

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  1. 1

    Emerging Insights into the Relationship Between Amino Acid Metabolism and Diabetic Cardiomyopathy by Yi Wen, Xiaozhu Ma, Shuai Mei, Qidamugai Wuyun, Jiangtao Yan

    Published 2025-06-01

    Diabetes mellitus (DM) is a complex global pandemic that frequently leads to multiple complications. Diabetic cardiomyopathy (DCM) is the primary cause of heart failure in patients with type 1 and 2 diabetes and is fundamentally characterized by abnormalities in myocardial structure and function. Me...

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    Subjects: “…amino acid metabolism…”
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  2. 2

    The Molecular Basis of Amino Acids Sensing by Cong Jiang, Xiao Tan, Jiali Jin, Ping Wang

    Published 2025-07-01

    Abstract Amino acids are organic compounds that serve as the building blocks of proteins and peptides. Additionally, they function as bioactive molecules that play important roles in metabolic regulation and signal transduction. The ability of cells to sense fluctuations in intracellular and extrace...

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    Subjects: “…amino acid sensing…”
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  3. 3

    Amino acids shape the metabolic and immunologic landscape in the tumor immune microenvironment: from molecular mechanisms to therapeutic strategies by Ziyou Lin, Chang Chang, Shuyu Zhao, Lan Fang, Ping Wang

    Published 2025-07-01

    The tumor immune microenvironment (TIME) represents a complex battlefield where metabolic competition and immune evasion mechanisms converge to drive cancer progression. Amino acids, with their multifaceted biological roles, have emerged as pivotal regulators of tumor cell proliferation and immune c...

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  4. 4

    Revisiting D‐Acylases for D‐Amino Acid Production by Sergio Martínez‐Rodríguez, Jose Antonio Gavira

    Published 2025-06-01

    ABSTRACT N‐Acyl‐D‐amino acid deacylases (EC 3.5.1.81, also known as D‐acylases) have been studied for decades for their utility in the kinetic resolution of N‐acetyl‐D,L‐amino acids (NAAs) due to a marked stereospecificity. In conjunction with an N‐succinyl‐amino acid racemase (NSAR), they impulse t...

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  5. 5

    Metabolic Response of Pakchoi Leaves to Amino Acid Nitrogen by Xiao-li WANG, Wen-juan YU, Qian ZHOU, Rui-feng HAN, Dan-feng HUANG

    Published 2014-04-01

    Different nitrogen (N) forms may cause changes in the metabolic profiles of plants. However, few studies have been conducted on the effects of amino acid-N on plant metabolic profiles. The main objective of this study was to identify primary metabolites associated with amino acid-N (Gly, Gln and Ala...

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  6. 6

    Changes in the amino acid pool in the rat parietal lobe and hippocampus with incomplete cerebral ischemia by E. I. Bon, N. Ye. Maksimovich, E. M. Doroshenko, V. Yu. Smirnov, M. A. Danilevich, A. S. Golushko

    Published 2023-12-01

    Introduction. Amino acids and their derivatives are involved in synaptic transmission as neurotransmitters and neuromodulators, and some of them are involved in the formation of neurotransmitters of the nervous system. Therefore, the study of the state of the amino acid pool in incomplete cerebral i...

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  7. 7

    CHEMICAL COMPOSITION AND AMINO ACID PROFILE OF FRESH AND STEAMED COBIA (Rachycentron canadum L.) by Nurjanah Nurjanah, Ruddy Suwandi, Taufik Hidayat, Vini Oktorina

    Published 2020-07-01

    <p>Cobia (<em>Rachycentron canadum</em>) is economically important fish with good prospects because of fast growing and easily cultured. Cobia is usually processed by many methods including steaming. The purposes of this research were to determine the effect of steaming process on...

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    Subjects: “…amino acid, cobia, essential, nonessential, steaming…”
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  8. 8

    ELECTROCHEMICAL INFLUENCE OF AMINO ACIDS ON THE CORROSION OF BIOALLOYS by Safija Herenda, Merima Begović, Edhem Hasković, Vanja Asanović

    Published 2024-12-01

    Shape memory alloys are of great commercial importance from biomedical applications to smart materials. The electrochemical behavior of Cu-Al-Zn alloy in phosphate buffer without and in the presence of amino acid was investigated. Electrochemical researches were performed in a traditional three-elec...

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  9. 9

    From Logs to Bags: A Metabolic Blueprint of Sanghuang Cultivation Revealed by UPLC-Q-TOF-MS/MS and Amino Acid Profiling by Kefan Xu, Lingli Chen, Chenchen Wu, Haiyang Wang, Fei Wu, Jingzhe Pu, Yazhong Zhang

    Published 2025-07-01

    Sanghuang (SH), a natural fungal resource used for food and medicinal purposes, has drawn considerable attention due to its pharmacological effects and efficacy. This study focused on Wild Sanghuang (WS) and Sanghuang cultivated using two different methods: Duanmu Sanghuang and Mycelium Sanghuang. U...

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  10. 10

    Phenylalanine modulates casein synthesis in bovine mammary epithelial cells by influencing amino acid transport and protein synthesis pathways by Yuanyuan Xing, Yuanyuan Xing, Yuanyuan Xing, Yixuan Luo, Yixuan Luo, Mei Sun, Mei Sun, Jing Yang, Jing Yang, Shaoxiong Lin, Shaoxiong Lin, Xiaojia Mu, Xiaojia Mu, Xiaoyu Niu, Xiaoyu Niu, Dabiao Li, Dabiao Li, Dabiao Li, Yuanyuan Liu

    Published 2025-07-01

    The efficiency of phenylalanine (Phe) utilization for milk protein synthesis in dairy cows is limited, and its uptake and metabolic mechanisms in the mammary tissue remaining unclear. This study investigated the effects of Phe availability (0.07, 0.14, 0.28, and 0.56 mM) on amino acid metabolism and...

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  11. 11

    Structural information of trypsin isozyme GT-B from grass carp (Ctenopharyngodon idellus) intestines by LIU Zhong-yi, WANG Zhang, XU Shi-ying, ZHANG Jian

    Published 2008-05-01

    In order to learn the correlation between chemical composition, structure and properties of grass carp intestine trypsin isozyme GT-B, the composition of amino acids, characteristic of ultraviolet absorption, and secondary structural units of this enzyme were investigated by instrumental and chemica...

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  12. 12

    A Study of the thermodynamic parameters (functions) of complexes formation of Sulfanilamid with metal ions and DL-Alanine by potentiometric method by Luma Abaas Gaasm

    Published 2019-05-01

    The current study deals with the preparation of disulfonalmide complexes composed of the sulfanilamid  drug , the salt of chromium(III) and the trisulfonalmide complexes composed of the  sulfonalmide drug , the metal salt and the amino acid (alanin), as well as study in the stability constant of ea...

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  13. 13

    Blood serum amino acid pool violation of in patients with liver cirrhosis by O. P. Balazh

    Published 2021-03-01

    Objective. To investigate serum amino acid pool changes in patients with liver cirrhosis. Materials and methods. 95 patients with liver cirrhosis were participated in the study. In the 1st group (class A disease severity according to Child- Pugh score) there were 18 (18.95%) patients, in the 2nd ...

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    Subjects: “…liver cirrhosis; amino acid pool; intestinal dysbiosis.…”
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  14. 14

    Asparagine Synthetase Gene <i>OsASN2</i> Is Crucial for Rice Seed Development and Germination by Rui Hu, Kaiming Liang, Xiangyu Hu, Meijuan Li, Qunhuan Ye, Yuanhong Yin, Cai Tang, Xinyu Wang, Youqiang Fu, Junfeng Pan, Mingyong Zhang, Xuhua Zhong

    Published 2025-06-01

    Seed development plays a critical role in determining both crop yield and grain quality in rice. As a key nutrient storage organ, the rice endosperm development not only contributes to grain filling but also plays an essential role during the early stages of seed germination. Amino acid metabolism i...

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  15. 15

    Quality variation of house cricket (Acheta domesticus) powder from Thai farms: Chemical composition, micronutrients, bioactive compounds, and microbiological safety by Parinya Boonarsa, Apichaya Bunyatratchata, Onanong Phuseerit, Nonthanan Phonphan, Theeraphan Chumroenphat, Ananya Dechakhamphu, Pornpisanu Thammapat, Teeraporn Katisart, Sirithon Siriamornpun

    Published 2025-07-01

    This study assessed the quality of house cricket (Acheta domesticus) powders sourced from three farms in Thailand, focusing on composition, bioactive compounds, and microbiological safety. The powders contained high protein (59–60 g/100 g DW), lipids (19–20 g/100 g DW), and essential amino acid inde...

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  16. 16

    Heating Experiments on Benthic Foraminifera Ammonia sp. to Assess the Suitability of Amino Acid-Based Dating by Rahmadi Hidayat, Didit Hadi Barianto, Sugeng Sapto Surjono, Che Aziz Ali

    Published 2024-09-01

    Sub-milligram fossil biominerals, mainly benthic foraminifera, have been recently used to estimate the age of sediments determined from amino acid dating due to the minimum sample size requirement for reverse-phase high-performance liquid chromatography (RP-HPLC). This includes the collection of Amm...

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    Subjects: “…amino acid racemization…”
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  17. 17

    Progress of research on microbiological chitosanases by DAI Yun, ZHU Xu-fen

    Published 2004-03-01

    Chitosan is one of the most abundant polysaccharides in nature. It consists of β-1, 4-linked D-glucosamine (GlcN) and N-acetyl-β-Dglucosamine (GlcNAc) residues. Chitosanases catalyze the hydrolytic breaking of its glucosidic bond and produce chitosan, which are widely applied for various purposes in...

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  18. 18

    Effect of graded levels of fiber from alfalfa meal on apparent and standardized ileal digestibility of amino acids of growing pigs by Liang CHEN, Li-xiang GAO, Li LIU, Ze-ming DING, Hong-fu ZHANG

    Published 2015-12-01

    Two experiments were conducted to determine the effects of fiber level from alfalfa meal and sampling time on the apparent ileal digestibility (AID) and standardized ileal digestibility (SID) of amino acids (AA) in growing pigs. A total of 24 ileal-cannulated pigs (Duroc×(Large White×Landrace) with...

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  19. 19

    Observation on changes of trace elements and amino acids in serum of patients with hepatocellular carcinoma by LUO Xi, JIANG Yongmei, MA Di, LU Qiuya, GU Xiaohan

    Published 2025-03-01

    Objective To explore the changes in trace elements and amino acid profiles in serum of patients with hepatocellular carcinoma(HCC) providing a reference for clinical diagnosis and treatment.Methods A total of 104 patients with HCC who underwent surgical treatment in the Department of Hepatobiliary...

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    Subjects: “…|hepatocellular carcinoma(hcc)|trace element|amino acid…”
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  20. 20

    Role of amino acids in the regulation of hepatic gluconeogenesis and lipogenesis in metabolic dysfunction-associated steatotic liver disease by Eiji Kakazu, Masaaki Mino, Tatsuya Kanto

    Published 2025-07-01

    Metabolic dysfunction-associated steatotic liver disease (MASLD) and its relatively advanced form, metabolic dysfunction-associated steatohepatitis (MASH), are becoming increasingly prevalent worldwide, making their prevention and management an urgent global health priority. Central to their develop...

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