Результаты поиска - Lung function

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Lung cancer ranks as the first most common cancer and the first leading cause of cancer-related death in China and worldwide. Due to the difficulty in early diagnosis and the onset of cancer metastasis, the 5-year survival rate of lung cancer remains low. JAK2 has emerged as pivotal participant in b...

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The results of numerous medical studies and kinesiology research show the existence of differences in the lung function with reference to age, body height and the ratio of certain parameters of body composition. The aim of this research is to determine the status of morphological characteristics and...

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Background. It is known that obesity may influence the state of respiratory function and it is associated with a number of diseases of the respiratory system. Obesity in itself, even in the absence of other known causes, can cause a feeling of shortness of breath at rest. At the same time, the cardi...

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Breathing reserve (BR) is the remaining proportion of achievable minute ventilation that remains unutilized at total exhaustion during exercise. Previous studies have found a smaller BR in endurance-trained athletes compared to untrained controls. However, most of these studies have examined men. Gi...

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This literature review is devoted to the analysis of the role of macrophages in the immunopathogenesis of infectious lung diseases of bacterial etiology. The article summarizes information about the origin of macrophages, their phenotypic and functional heterogeneity. The mechanisms of impaired prot...

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The systemic inflammatory response is an integral part of any cardiac surgery during which an out-of-body blood stream machine is used. During the operation, the blood is exp sed to a foreign body belonging to the tubes themselves, which are part of the extracorporeal bloodstream and this is the rea...

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ObjectivesMagnetic resonance imaging (MRI) of the lung is well suited for repeated measurements especially in children due to the absence of ionizing radiation. Furthermore, non-contrast-enhanced (NCE) functional MRI techniques provide localized functional information on ventilation and perfusion wi...

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Aim. To study the ventilation function of the lungs in patients with varying degrees of severity of chronic obstructive pulmonary disease (COPD) and in patients with COPD combined with lung cancer (LC), as well as to establish the features of its disorders using spirography and body plethysmography....

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Objective – the role of immunosuppressive mechanisms in the correction of respiratory system dysfunctions associated with autoimmune pathology (antiphospholipid syndrome). The aim of the study was to study the effect of the immunosuppressive drug fingolimod on non-respiratory functions of the lungs...

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Background: It is thought that swimming might elicit remarkable chronic lung function improvements that were not observed in land-based sports. However, there is no consensus on whether this is mainly attributable to genetic predisposition or specific training. This study aimed to characterize athle...

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Background: Spirometry interpretation after lung transplantation (LTx) is complex, requiring a clear understanding of reference values and normal thresholds globally. Abnormal values are typically based on general population reference standards. Methods: In April 2025, a 10-question online survey wa...

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Aim. To study clinical and morphofunctional indicators of respiratory function in patients with dilated cardiomyopathy (DCM) with and without pulmonary hypertension (PH).Material and methods. 91 patients with idiopathic DCM (34 women and 57 men; mean age of 46.4±13.7 years) were included into the st...

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Among the chronic nonspecific lung diseases, bronchial asthma (BA) takes the leading place. BA in children is primarily diagnosed on the basis of clinical manifestations, methods of functional diagnosis, which allows you to verify the disease and assess the severity of the flow. An important role in t...

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BACKGROUND: The long-term effects of pulmonary TB (PTB) on pediatric lung health are poorly understood. Our objective was to assess predictors of lung function and describe health-related quality of life (QoL) and chest radiograph findings in children following PTB treatment in Kampala, Uganda. METH...

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A rare but important complication after lung transplantation (LTx) is postoperative phrenic nerve dysfunction (PND). Diaphragmatic plication (DP) is a well-established treatment option for PND, however, the long-term effect of PND and DP on lung function parameters and survival after LTx are current...

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Study objective. Evaluation of the possibilities of ventilation and perfusion scintigraphy in detecting functional disorders and determining the severity of lung damage that may occur after organ transplantation. Material and methods. The study included 27 patients after bilateral lung transplantati...

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N6-methyladenosine (m6A) is the best-studied post-transcriptional RNA modification. It refers to the methylation in the N6 position. M6A exists universally from viruses to mammalian cells and is highly abundant in RNA polymerase II-transcribed, protein-coding transcripts and various non-coding RNAs....

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Non-small cell lung cancer (NSCLC), as the main histological subtype of lung cancer, has consistently ranked among the top malignant tumors in terms of incidence and mortality worldwide. With the advancement of high-throughput sequencing and proteomics technologies, the regulatory roles of deubiquit...

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