Rezultaty - "atopic dermatitis"

The report presents the results of the IL4 and IL10 serum levels investigation in patients with atopic dermatitis during the exacerbation of the disease and after phototherapy, as well as in comparison with healthy donors. The obtained results showed higher concentrations of IL10 in patients with at...

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Introduction and purpose The subject of this article is the role of the skin microbiome in the pathogenesis of atopic dermatitis - the current state of knowledge. As is known, the skin plays a key role in protecting the body and maintaining homeostasis, cooperating with the microbiome, which affect...

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The article analyzes the current data on the pathogenesis of atopic dermatitis. It discusses the role of the damaged dermal barrier structure in the development of food allergies and presents the results confirming the theory of transdermal sensibilisation to allergens in addition to hereditary and...

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Introduction. The instructions for the drug dupilumab indicate that the administration of a single loading dose on the first day leads to the rapid achievement of clinically effective concentrations within 2 weeks, which we saw in the example of our patient and her real clinical response to the firs...

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Aim. To improve the diagnosis of allergic skin diseases in childrenMaterials and methods. 135 children aged from 2 to 6 with atopic dermatitis were examined during exacerbation. They were on inpatient treatment in the skin and venereologic department of the Regional skin and venereologic dispensary...

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The peculiarity of the skin is that it acts not only as a place of synthesis of vitamin D, but also as an organ targeted for its biologically active form. The aim of our study was to analyze the level of vitamin D in patients with atopic dermatitis. There were examined 48 people aged between 18 to...

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Background: Atopic dermatitis (AD) is an important issue, significance of which is determined by the incidence increase, chronic, relapsing course of the disease, and poor treatment efficacy.Objective: Our aim was to study clinical efficacy of enterosorbent based on pectin, inulin and fennel extract...

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Results of the genetic typing and immunologic analysis in patients with atopic dermatitis are presented. Various genetic polymorphisms in genes of GST (M1, T1 and P1) were described in patients with atopic dermatitis. The whole set of the results obtained indicates the necessity to pay attention to...

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Atopic dermatitis (AD) is a disease characterized by chronic skin inflammation and epidermal barrier dysfunction leading to decrease in patients' quality of life. AD is widespread in general population including children. This article covers the disease pathophysiological mechanisms including t...

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Atopic dermatitis, a common chronic inflammatory skin disease, has an unclear etiology and may involve multiple factors such as genetic predisposition, immune abnormalities, and impaired skin barrier function. Currently, there is no specific medication available for the complete cure of atopic derma...

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Atopic dermatitis remains an important medico-social problem due to its high spread in the population and development of complications. External non-steroid therapy remains first line treatment. This article presents treatment results of 40 patients aged 1 to 17 years old with moderate to severe ato...

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Abstract Background Atopic dermatitis is a common chronic skin disease in children. Whether telomere length is associated with atopic dermatitis remains unclear. This population‐based case‐control study aimed to investigate the association between telomere length and atopic dermatitis in school‐age...

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Abstract Introduction Children with atopic dermatitis (AD) bear a significant burden of illness that adversely affects their quality of life. Objective To determine the efficacy of dupilumab and topical corticosteroids for the treatment of pediatric AD. Methods A comprehensive literature search was...

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There have been defined IL-4, IL-10, IL-17 and IFN-γ in cell-free skin exudate in 90 patients of atopic dermatitis depending on spread of dermal pathological process. There been found that variations of each cytokine had different features and reflected different parts of immunopathogenesis of the d...

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Introduction. It is believed that if the child ate only a cow’s milk formula (CMF), and сow’s milk allergy is the only possible at the age of <6 months. This approach leads to erroneous treatment tactics.   Presentation of the clinical case. A child aged 3 months with the debut of atopic derm...

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The problem of polymorbidity in dermatological practice conditions the need for careful compliance with the diagnostic algorithm and analysis to identify the possibility of etiopathogenetic interconnection of diseases and their impact on each other. In this article we present a case of rare combined...

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Introduction. Atopic dermatitis (AtD) is a genetically determined chronic dermatosis with heterogeneous manifestations that can significantly affect the quality of life of patients. The disease has a complex pathogenesis, which significantly complicates its treatment. The JAK-STAT signaling pathway...

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Objective: The aim of our study was to compare the effectiveness and tolerability of desloratadine solution vs syrup formulation in children with atopic dermatitis. Methods: Children of the 1st group received desloratadine solution and children of the 2nd group received desloratadine syrup 1,25 mg o...

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Purpose: Research of certain peculiarities of the clinical course of atopic dermatitis in children’s early age.Materials and Methods: A total of 30 children in early age with the clinical manifestations of atopic dermatitis were involved in the investigation.Results and Summary: It was found that сl...

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The role of transforming growth factor β (TGF-β) in atopic dermatitis pathogenesis is discussed basing on the analysis of existing data of cellular and molecular mechanisms of allergic inflammation. Up-to date data of the main T-helper (T-h) lymphocyte subpopulations including Tx1, Tx2, Tx3 has been...

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