Torthaí cuardaigh - Michelle Wu
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Testing job wellbeing indicators among community behavioral health workers: Community-based participatory research.
Foilsithe / Cruthaithe 2025-01-01Faigh an téacs iomlánMany community behavioral health organizations (CBHOs) continue to struggle with their employees' reduced job wellbeing and job disengagement (i.e., turnover intentions, actual turnover). Understanding employees' job wellbeing priorities in their organizational contexts is essential to add...
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Pain, fatigue, and associated gene expressions over chemotherapy in patients with colorectal cancer
Foilsithe / Cruthaithe 2025-01-01 Faigh an téacs iomlán
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Pain, fatigue, and associated gene expressions over chemotherapy in patients with colorectal cancer.
Foilsithe / Cruthaithe 2025-01-01Faigh an téacs iomlán<h4>Context</h4>Patients with colorectal cancer undergoing chemotherapy often experience significant pain and fatigue. Limitations in understanding the complex phenotypes and biological mechanisms of these symptoms hinder effective interventions.<h4>Objectives</h4>This study...
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Unveiling the Reactivity of Fluoropolymers with Sodium Metal: Mechanistic Insights and Battery Implications
Foilsithe / Cruthaithe 2025-06-01 Faigh an téacs iomlán
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Anti-Dengue Activity of Revaprazan Hydrochloride: A Repurposed Drug Candidate
Foilsithe / Cruthaithe 2025-07-01Faigh an téacs iomlánDengue fever is a major health problem, and there are no vaccines or effective antiviral treatments. Drug repurposing is a quick and appealing innovative therapeutic strategy. This study aims to develop a potent anti-dengue drug for the treatment of dengue infections. In this study, we screened a l...
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Agile User-Centered Design of a Clinical Research Project Management System in a Pediatric Health Institute
Foilsithe / Cruthaithe 2025-07-01 Faigh an téacs iomlán
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Non-invasive Diagnosis of Antinephrin–Associated Podocytopathy
Foilsithe / Cruthaithe 2025-08-01Faigh an téacs iomlánIntroduction: Circulating autoantibodies against the podocyte surface protein nephrin have recently been described in patients with podocytopathies, that is, minimal change disease, primary focal segmental glomerulosclerosis, and childhood idiopathic nephrotic syndrome. Their high specificity for po...
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Systematic review of HIV transmission between heterosexual serodiscordant couples where the HIV-positive partner is fully suppressed on antiretroviral therapy.
Foilsithe / Cruthaithe 2013-01-01Faigh an téacs iomlán<h4>Background</h4>The risk of sexual HIV transmission in serodiscordant couples when the HIV-positive partner has full virologic suppression on combination antiretroviral therapy (cART) is debated. This study aims to systematically review observational studies and randomized controlled...
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Microbial hallmarks of the respiratory tract in lung cancer: a meta-analysis
Foilsithe / Cruthaithe 2025-07-01Faigh an téacs iomlánIntroductionLung cancer is a leading cause of cancer-related deaths and has been associated with the microbiota of the human respiratory tract. However, the optimal sample type for studying the role of microbiota in lung cancer and the microbial hallmarks of lung cancer patients remain unclear. Meth...
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Plasma microRNA signatures of aging and their links to health outcomes and mortality: findings from a population-based cohort study
Foilsithe / Cruthaithe 2025-06-01Faigh an téacs iomlánAbstract Background MicroRNAs are small non-coding RNAs that regulate gene expression post-transcriptionally and show differential expression in various tissues with aging phenotypes. Detectable in circulation, extracellular microRNAs reflect (patho)physiological processes and hold promise as biomar...
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Biomechanics associated with bone stress injury in athletes differ by proximal and distal anatomical locations: a cross-sectional analysis
Foilsithe / Cruthaithe 2025-06-01Faigh an téacs iomlánBackground Bone stress injury (BSI) is a common overuse injury in female athletes that can occur in a variety of bones, including both proximal (pelvis, sacrum, femoral neck) or distal (tibia, fibula, metatarsals) locations. Prior work has demonstrated differences in running biomechanics in those wi...
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Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility.
Foilsithe / Cruthaithe 2018-01-01Faigh an téacs iomlánEpithelial ovarian cancer (EOC) is the fifth leading cause of cancer mortality in American women. Normal ovarian physiology is intricately connected to small GTP binding proteins of the Ras superfamily (Ras, Rho, Rab, Arf, and Ran) which govern processes such as signal transduction, cell proliferati...
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A whole-brain voxel-based analysis of structural abnormalities in PTSD: An ENIGMA-PGC study
Foilsithe / Cruthaithe 2025-01-01Faigh an téacs iomlánAbstract Background Patients with posttraumatic stress disorder (PTSD) exhibit smaller regional brain volumes in commonly reported regions including the amygdala and hippocampus, regions associated with fear and memory processing. In the current study, we have conducted a voxel-based morphometry (...
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Effects of empagliflozin on quality of life and healthcare use and costs in chronic kidney disease: a health economic analysis of the EMPA-KIDNEY trialResearch in context
Foilsithe / Cruthaithe 2025-07-01Faigh an téacs iomlánSummary: Background: Sodium-glucose co-transporter 2 inhibitors (SGLT2i) slow progression of chronic kidney disease (CKD) but there is no randomised evidence of their effects on health-related quality of life (QoL) and healthcare use. We explored the effects of empagliflozin on health-related QoL,...
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