Torthaí cuardaigh - FIASCO
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From abciximab to abelacimab. Subjective surfing upon discoveries and fiascos of biological therapies in cardiology
Foilsithe / Cruthaithe 2025-07-01Faigh an téacs iomlánThe author happened to be involved in the discovery and assessment of biological therapies, which are otherwise uncommon in the field of cardiology. Thus, he has the opportunity to draw some conclusions from his experience and, at the same time, shed light on instructive research dead ends and failu...
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A FIASCO-Based Approach for Detection and Diagnosis of Puccinia graminis f. sp. tritici in China
Foilsithe / Cruthaithe 2014-11-01Ábhair: Faigh an téacs iomlánStem or black rust of wheat, caused by the fungus Puccinia graminis Pers. f. sp. tritici Eriks. & E. Henn. (Pgt), has historically caused severe losses to wheat (Triticum aestivum L.) production worldwide. In the Fujian and Guangdong provinces of China, six moderate-to-severe epidemics of wh...
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Development of SSR Markers for a Phytopathogenic Fungus, Blumeria graminis f.sp. tritici, Using a FIASCO Protocol
Foilsithe / Cruthaithe 2014-01-01Ábhair: Faigh an téacs iomlánSimple sequence repeats (SSR) have been widely used as molecular markers due to their abundance and high polymorphism. However, up to now, the SSR markers had not been developed in the obligate biotrophic phytopathogenic fungus, Blumeria graminis f.sp. tritici. From (AC)10 and (AG)10 enriched genomi...
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Russian–Japanese Relations at the Turn of the Century: Patterns, Routes, Leaders
Foilsithe / Cruthaithe 2021-08-01“…Nevertheless, even here Tokyo faced a fiasco. Before the arrival of the Abe era in late 2012, Japan’s foreign policy toward Russia became increasingly “reactive,” and even later Tokyo’s high-profile initiatives related to the Russian-Japanese agenda often turned out to be old proposals from Moscow that had been made during the time of Michael Gorbachev, and favorable moments for their implementation were largely missed.…”This article analyzes why, during the post-Cold War period, Tokyo became aware of the need to reconsider its hard-line relations with Moscow, which had been developed in previous decades. Even in the period preceding the collapse of the USSR, Tokyo did not conceal its intentions to use the difficult s...
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CONSTITUTIONAL AND LEGAL DEVELOPMENT OF THE REPUBLIC OF THE PHILIPPINES AND PECULIARITGIES OF THE 1987 CONSTITUTION
Foilsithe / Cruthaithe 2013-08-01“…The author shows that the U.S. attempts to impose its former colony model of American state and legal institutions that would facilitate the establishment of the South- East Asia "window of Western democracy", and could serve as a role model for the layout of other countries, not only in South-East Asia but also in Africa and Latin America, suffered a fiasco.…”The article analyzes the stages of constitutional development of the Philippines, the principles and characteristics of the various constitutional acts adopted in the American colonial period and after the country's legal independence. Particular attention is paid to the principles and the spec...
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Management of the business system of the enterprise
Foilsithe / Cruthaithe 2022-12-01“…An attempt to build a business system based on "crooked" business processes ends in fiasco.…”The article is devoted to topical issues of the development of modern enterprises. Today, one of the main elements of the profitability of any production is the rational management of the enterprise's business system. The business system is one of the innovative forms of ensuring the competitiv...
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WHY WE CANNOT PREDICT STRONG EARTHQUAKES IN THE EARTH’S CRUST
Foilsithe / Cruthaithe 2015-09-01“…Lesson should be learned from our common fiasco in forecasting, taking into account research results obtained during the past 50–60 years. …”In the past decade, earthquake disasters caused multiple fatalities and significant economic losses and challenged the modern civilization. The wellknown achievements and growing power of civilization are backstrapped when facing the Nature. The question arises, what hinders solving a problem of ear...
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