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  1. 1

    White matter structural changes in the visual pathway of thyroid-associated ophthalmopathy patients: a free water and multi-shell diffusion imaging study Tekijä Jiaqi Yao, Jiaqi Yao, Xinjian Lu, Jingxu Ma, Lu Hao, Ying Liu, Xiaopan Huang, Jun Liu, Boding Tong

    Julkaistu 2025-06-01

    BackgroundCompared to single-shell diffusion tensor imaging (DTI), free water (FW) and neurite orientation dispersion and density imaging (NODDI) offer a more comprehensive evaluation of microstructural alterations in cerebral white matter (WM), particularly in detecting crossing fibers. However, re...

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    The influence of family in children’s feeding difficulties: an integrative review Tekijä Pâmela Gracielle da Fonseca, António Raposo, Nada Alqarawi, Ibrahim Alasqah, Mariana Figueiredo Pinto, Tábata Monaliza Marcelino Martins, Viviane Dias Gonçalves, Simone Cardoso Lisboa Pereira, Najla A. Albaridi, Mona N. BinMowyna, Ariana Saraiva, Ariana Saraiva, Nathalia Sernizon Guimarães

    Julkaistu 2025-07-01

    BackgroundFeeding difficulties, such as limited appetite, selective eating, and food phobia, affect caregivers' ability to provide adequate nutrition to children. These issues impact 25%–40% of non-neurodivergent children and up 80% of neurodivergent children.AimThis review examines how family...

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    Primary giant hepatic neuroendocrine neoplasms in a young adult: case report and literature review Tekijä Xue Luo, Xingxing Bie, Na Luo, Wenting Huang

    Julkaistu 2025-07-01

    Primary hepatic neuroendocrine neoplasms (PHNENs) are a rare type of neuroendocrine tumors originating in the liver. These tumors are characterized by non-specific clinical symptoms and atypical imaging features, making differentiation from other primary hepatic masses, such as hepatocellular carcin...

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  5. 5

    Diagnostic accuracy of neutrophil-to-lymphocyte ratio in type 2 diabetic nephropathy: a meta-analysis Tekijä Yan Wang, Xiaohua Liu, Zhenwen Xiao

    Julkaistu 2025-07-01

    BackgroundDiabetic nephropathy (DN) represents one of the most prevalent microvascular complications of type 2 diabetes mellitus (T2DM). The pathogenesis of DN is significantly influenced by the inflammatory response. Thus, the current meta-analysis aimed to assess the diagnostic accuracy of neutrop...

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    Teachers’ experiences with the Back2School intervention—a pilot study addressing problematic school absenteeism Tekijä Elisabeth Valmyr Bania, Toril Sørheim Nilsen, Mikael Thastum, Jo Magne Ingul, Trude Havik

    Julkaistu 2025-08-01

    IntroductionSchool absenteeism represents a concern for students, educators, and parents alike. Teachers’ involvement is vital to students’ school life. Consequently, integrating schools and teachers effectively in absenteeism interventions is of great importance. However, few studies have investiga...

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    Evaluating the WHO leadership in emergencies training programme: participants' perspective Tekijä Celine Tabche, Zeenah Atwan, Samar Al-Mutawakel, Noémie Andriamiseza, Maria Popovich, Ela Augustyniak, Andrew Black, Heini Utunen, Salman Rawaf

    Julkaistu 2025-07-01

    BackgroundThe Leadership in Emergencies (LIE) training programme, developed by WHO's Health Emergencies (WHE) Learning and Capacity Development Unit (LCD) and Eastern Mediterranean Region (EMR) Health Emergencies Department, aims to enhance emergency management and responders' technical an...

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    Thoracoscopic right anterior basal segmentectomy with unique anatomic variation: a case report and literature review Tekijä Tiancheng Liu, Tiancheng Liu, Sishi Huang, Sishi Huang, Jianbin Zhang, Jianbin Zhang, Lili Jin, Lili Jin, Qibin Shen, Qibin Shen

    Julkaistu 2025-06-01

    BackgroundAnatomic basal segmentectomy is often regarded as a complex procedure, particularly in the presence of complex anatomical variations.Case reportHerein, we present a case of a 55-year-old female patient diagnosed with invasive lung adenocarcinoma. Three-dimensional computed tomography bronc...

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    Nickel nanoparticles: a novel platform for cancer-targeted delivery and multimodal therapy Tekijä Fengyu Wang, Fengyu Wang, Sen Tong, Sen Tong, Xuan Ma, Xuan Ma, Huan Yang, Huan Yang, Tianbao Zhang, Tianbao Zhang, Kunrong Wu, Kunrong Wu, Junzi Wu, Junzi Wu

    Julkaistu 2025-07-01

    Traditional cancer treatment methods often encounter limitations, such as poor targeting, low bioavailability, and high systemic toxicity. These challenges have led researchers to explore alternative therapeutic strategies. Nickel nanoparticles (NiNPs), owing to their distinctive physicochemical pro...

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    Time-dependent effects of calcium oxide on urban sludge dewatering in temporary lagoons and its application in sustainable urban development Tekijä YunTian Zhou, Changfu Huang, Yuan Wang, Xiaoming Zhao, Huanqiang Luan, Shuailong Zhang

    Julkaistu 2025-07-01

    Calcium oxide (CaO) was used to condition urban sludge, with a focus on the impact of conditioning time, and its potential application in sustainable urban development was explored. In this study, the volume reduction ratio (VRR) was employed as the primary evaluation metric, and response surface me...

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    Effects of activated carbon and four different biochars on fermentation in the artificial rumen (RUSITEC) Tekijä Alexander Weinberg, Franziska Witte, Dana Carina Schubert, Karl Rohn, Martin Hoeltershinken, Victoria Eva Hancock, Werner Sitzmann, Nino Terjung, Christian Visscher

    Julkaistu 2025-07-01

    Anthropogenic climate change is primarily caused by CO2 and CH4 emissions, with a significant portion originating from agriculture and livestock. Reducing methane emissions in ruminant husbandry has been a longstanding goal. Therefore, in this study, we aimed to influence the fermentation processes...

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    CXCL16/CXCR6 axis arises as a potential peripheral biomarker of early COPD development – results from a pilot study Tekijä Patrice Marques, Patrice Marques, Patrice Marques, Irene Bocigas, Elena Domingo, Elena Domingo, Vera Francisco, Julia Tarrasó, Julia Tarrasó, Laura Piqueras, Laura Piqueras, Laura Piqueras, Jaime Signes-Costa, Jaime Signes-Costa, Cruz González, Cruz González, Maria-Jesus Sanz, Maria-Jesus Sanz, Maria-Jesus Sanz

    Julkaistu 2025-07-01

    BackgroundChronic obstructive pulmonary disease (COPD) is mainly caused by long-term exposure to cigarette smoke. Since systemic inflammation is an important component of COPD pathophysiology, its characterization is essential for developing new biomarkers and pharmacological approaches. We have pre...

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    Genotype-by-environment interaction influencing sensory attributes and biochemical components of peanuts from China Tekijä Yueyi Tang, Shining Cao, Chushu Zhang, Weidong Hu, Haixiang Zhou, Mian Wang, Lifei Zhu, Jing Chen, Jun Zhang, Jiancheng Zhang

    Julkaistu 2025-08-01

    BackgroundPeanuts are a vital global crop and healthy food, valued for their nutritional and physiological benefits. Their sensory attributes and biochemical composition, which determine taste and nutritional quality, are influenced by multiple factors. Thirteen peanut genotypes were cultivated acro...

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    Improving stroke awareness through a culturally adapted audiovisual intervention in the United Arab Emirates Tekijä Michelle Cherfane, Michelle Cherfane, Michelle Cherfane, Jihan Safwan, Jihan Safwan, Chadia Haddad, Chadia Haddad, Chadia Haddad, Chadia Haddad, Hala Sacre, Hala Sacre, Pascale Salameh, Pascale Salameh, Pascale Salameh, Pascale Salameh, Rawan Elkerenawy, Tala Abou El Kheir, Mariam Al Nuaimi, Leen Abou Mattar, Hassan Hosseini, Fouad Sakr, Fouad Sakr, Katia Iskandar, Katia Iskandar, Katia Iskandar

    Julkaistu 2025-07-01

    ObjectivesThis study evaluates the effectiveness of a brief, culturally tailored educational video in improving stroke-related knowledge among residents of the United Arab Emirates (UAE).MethodsA pre-post intervention study was conducted with 407 UAE residents aged 25 years and older. Participants v...

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    “It just isn’t the same”: altered routines among older Americans three years after the COVID-19 pandemic onset Tekijä Rebecca A. Milan, Mallory A. P. Sagehorn, Mallory A. P. Sagehorn, Rohini Perera, Rohini Perera, Grace I. Bowman, Grace I. Bowman, Grace I. Bowman, Jessica Finlay, Jessica Finlay

    Julkaistu 2025-07-01

    IntroductionThe COVID-19 pandemic significantly disrupted civic life, particularly for older adults at increased risk for severe morbidity and mortality. Yet, little is known about the longer-term impacts on their daily routines and how this may affect health and wellbeing.MethodsThis qualitative st...

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    Genomic identification of recipient-derived hepatocytes in liver transplantation: a hypothesis linking graft repopulation to immune tolerance Tekijä Seoung Hoon Kim

    Julkaistu 2025-07-01

    BackgroundOperational tolerance, defined as stable liver graft function without immunosuppression, has been observed in select transplant recipients. While immune regulatory mechanisms have been implicated, the biological processes underlying tolerance remain incompletely understood. Notably, recipi...

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    Artificial liver plasma adsorption improves survival in elderly patients with severe pneumonia: a retrospective cohort study Tekijä Richai Chen, Jiaqian Jin, Sainan Zhang, Jiajun Wu, Qiangqiang Xiang, Xuanhao Lin, Danhua Zhu, Mengfei Zhu

    Julkaistu 2025-07-01

    ObjectiveTo assess the therapeutic efficacy of artificial liver plasma adsorption (ALPA) in patients with severe pneumonia.MethodsThis retrospective study enrolled 151 patients meeting severe pneumonia diagnostic criteria who were admitted to the intensive care unit at Shulan Hospital, Hangzhou, Chi...

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    Stereoacuity and ocular-associated factors in children aged 3–7 years in Guangxi, Southwest China: a cross-sectional study Tekijä Xin Xiao, Xin Xiao, Xin Xiao, Huiyao Huang, Yan Luo, Wuqiang Luo, Lili Li, Enwei Lin, Min Kong, Qi Chen

    Julkaistu 2025-07-01

    ObjectiveThis study aimed to investigate the distribution of stereoacuity and its ocular-associated factors in children aged 3–7 years in Guangxi, Southwest China.MethodsThis cross-sectional study recruited 4,090 children aged 3–7 years (mean: 5.12 ± 0.95 years) from 12 randomly selected kindergarte...

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    Water exchange in the Baltic Sea: a historical view of research approaches from basin scales to submesoscale Tekijä Jüri Elken, Anders Omstedt

    Julkaistu 2025-07-01

    At the beginning of the 20th century, Knudsen illustrated that the mean observed salinity of the Baltic Sea could be realistically estimated, assuming an inflow of saline Kattegat water equals the net freshwater supply, also called the Knudsen theorem. As given in the historical review, several stud...

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