Search Results - "microsatellite"
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Genetic diversity and phylogenetic relationship estimation of Shanxi indigenous goat breeds using microsatellite markers
Published 2024-12-01Subjects: Get full textThe objective of this study was to assess the genetic diversity, phylogenetic relationship and population structure of five goat breeds in Shanxi, China. High genetic diversities were found in the five populations, among which, Licheng big green goat (LCBG) has the highest genetic diversity, while J...
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Microsatellites reveal strong genetic structure in the common cutworm, Spodoptera litura
Published 2019-03-01Subjects: Get full textThe common cutworm, Spodoptera litura (Lepidoptera: Noctuidae), is a voracious agricultural pest. To increase understanding of the migration patterns and genetic diversity of different geographic populations of this species, we analyzed genetic variation in nine microsatellite loci among 576 individ...
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Diversity assessment of a lesser known buffalo population from Central India and its comparative evaluation reveals presence of sufficient genetic variation and absence of selectio...
Published 2024-12-01Subjects: Get full textPlanned breeding and conservation strategies for a lesser-known population require an assessment of complete genetic diversity and population structure analysis in addition to its morphometric characteristics. In the present study, a comparative analysis of the genetic structure of a rare buffalo po...
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Population Structure of the Dog Snapper, <i>Lutjanus jocu</i> (Bloch & Schneider, 1801), an Important Fishery Resource in the North of Bahia, Brazil: Influence of Habitat Suitabili...
Published 2025-06-01Subjects: Get full textThe Lutjanidae family includes multiple species highly important to the global fishing industry. In Brazil, approximately 40% of the fishing landings come from a species of this family, the dog snapper, <i>Lutjanus jocu</i>, among the most abundant in the northeast-region fisheries. This...
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Microsatellite instability (MSI, EMAST) in the pathogenesis of follicular lymphoma
Published 2021-06-01Subjects: Get full textBackground. Genetic instability, an important phenomenon involved in oncogenic transformation and tumor progression, is associated with the insufficiency of the multicomponent DNA repair complex, in particular, the nucleotide mismatch repair (MMR) system. The MMR defect manifests itself as abnormali...
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Assessment of genetic purity of cotton cultivars (Gossypium hirsutum L.) using morphological characteristics and microsatellite marker (SSR)
Published 2023-09-01Subjects: Get full textIn order to evaluate the genetic purity and originality of three common commercial cotton cultivars (Varamin, Khordad and Bakhtegan) using morphological characteristics and microsatellite markers, the seeds of these cultivars along with pure lines in the field in a two-year randomized complete block...
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Genetic variations among pacific herring (<i>Clupea pallasii Val</i>.) from the Okhotsk Sea and Lake Ainskoye by microsatellite loci
Published 2016-12-01Subjects: Get full textGenetic variation among spawning groups of pacific herring from different spawning grounds in the northwestern Okhotsk Sea and Lake Ainskoye (Sakhalin Island) is assessed by 11 microsatellite loci. All loci were polymorphic. Genetic differentiation of the herring from the Okhotsk Sea was statistical...
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Assessment of genetic purity of Iranian commercial maize hybrid seeds using DUS characteristics and microsatellite markers
Published 2020-01-01Subjects: Get full textGenetic purity is one of the most important qualitative criteria for success in hybrid seeds production. In order to avoid reduction in yield caused by using presence of seeds resulting from self-pollinating and unwanted crossing or seed mixing, development of a simple, rapid, and accurate method fo...
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Microsatellite instability as a reliable marker of coexisting endometrial cancer in atypical endometrial hyperplasia
Published 2024-07-01Subjects: “…microsatellite instability…”Background. Endometrial cancer (EC) dominates in the structure of gynecological cancer morbidity. There has been an increase in this nosology in women of reproductive age. The morphological precancerous form of endometrioid adenocarcinoma is endometrial intraepithelial neoplasia (EIN), or atypical e...
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Validation of high-throughput sequencing-based test system for detection of microsatellite instability in colorectal cancer samples
Published 2025-04-01Subjects: Get full textIntroduction. Currently in routine clinical practice, standard methods based on polymerase chain reaction (PCR) and immunohistochemical examination are used to determine microsatellite instability (MSI) and deficient mismatch repair system (dMMR). MSI identification using high-throughput sequencing...
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Medullary carcinoma of the pancreas radiologically followed up as a cystic lesion for 9 years: a case report and review of the literature
Published 2018-07-01Subjects: Get full textAbstract Background Medullary carcinoma of the pancreas (MCP) is a rare malignant pancreatic tumor. The World Health Organization classification defines the tumor as a subtype of pancreatic ductal carcinomas. MCP is histologically characterized as having highly pleomorphic cells with syncytial morph...
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Endangered with High Dispersal Abilities: Conservation Genetics of <i>Himantoglossum metlesicsianum</i> (Teschner) <i>P. Delforge</i> (Orchidaceae) in the Canary Islands
Published 2025-06-01Subjects: Get full text<i>Himantoglossum metlesicsianum</i> is a threatened orchid with low population numbers and fragmented distribution, present in four of the Canary Islands. This study focused on assessing the genetic variability and population genetic structure of the natural populations known to date, i...
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MICROSATELLITE-UNSTABLE COLORECTAL CANCER IN ELDERLY PATIENTS: CLINICAL FEATURES AND THE ROLE OF IMMUNODEFICIENCY
Published 2020-03-01Subjects: Get full textBackground. Tumors demonstrating the phenomenon of microsatellite instability (MSI) represent a special category of colorectal cancer (CRC). Such neoplasms account for up to 20 % of CRC and are characterized by specific molecular and clinical manifestations, including high immunogenicity and sensiti...
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Prognostic significance of PD-L1 expression and evaluation of microsatellite instability status in patients with retroperitoneal leiomyosarcomas
Published 2019-11-01Subjects: Get full textBackground. Leiomyosarcoma is one of the most common types of soft tissue sarcomas. Radical surgical resection with subsequent adjuvant chemotherapy remain the most effective treatment approach. Immunotherapy based on inhibition of PD-L1 (programmed death ligand 1) or its receptor PD1 (programmed de...
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Combination of pembrolizumab and lenvatinib in second-line therapy for MSS/pMMR advanced endometrial cancer: literature review and a case report
Published 2024-01-01Subjects: Get full textDespite the existing standard treatments for endometrial cancer, the prognosis for these patients remained poor until recently. None of currently available cytostatics ensured long-term disease control and long-term survival of patients receiving standard platinum-based therapy. Poor treatment outco...
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Аpplicability of microsatellite loci designed for cosmopolitan species for the investigation of endemic species: a case study of Silene sendtneri Boiss.
Published 2021-12-01Subjects: Get full textSilene sendtneri Boiss. (Caryophyllaceae) is the Dinaric endemic plant species with white, decorative and scented flowers. Previous studies on this endemic species were based on morphology and effects on seed germination after the treatment with salicylic acid. However, no molecular genetic studies...
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Development of SSR Markers for a Phytopathogenic Fungus, Blumeria graminis f.sp. tritici, Using a FIASCO Protocol
Published 2014-01-01Subjects: Get full textSimple sequence repeats (SSR) have been widely used as molecular markers due to their abundance and high polymorphism. However, up to now, the SSR markers had not been developed in the obligate biotrophic phytopathogenic fungus, Blumeria graminis f.sp. tritici. From (AC)10 and (AG)10 enriched genomi...
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MICROSATELLITE INSTABILITY AS A MOLECULAR GENETIC MARKER OF DEFECTIVE MISMATCH REPAIR SYSTEM IN ESOPHAGEAL CANCER
Published 2016-12-01Subjects: Get full textEsophageal cancer is an aggressive form of cancer. Adenocarcinoma and squamous cell carcinoma are the most common histological types of esophageal cancer, with the incidence rate showing an upward tendency. Although endoscopic biopsy is considered the «gold standard» for diagnosis of esophageal canc...
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DNA Identification of Biological Traces in Forensic Casework for Investigation of Illegal Hunting in Belarus
Published 2018-12-01Subjects: Get full textThe article discusses molecular genetic identification of biological traces of wild animals used in forensic casework of illegal hunting of representatives of the order Artiodactyla – moose, red deer, roe deer, wild boar, and European bison. The question of species identification as an essential sta...
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Genetic Variability and Population Structure of <i>Camelus</i> from Kazakhstan Inferred from 17 STR Markers
Published 2025-06-01Subjects: Get full textCamels have been essential to human survival and development across the arid Central Asian steppes, particularly in Kazakhstan, where the breeding of one-humped and two-humped camels is a longstanding tradition supporting the nomadic lifestyle. This study aimed to assess the genetic diversity and po...
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