Targeting Th9 cells in autoimmune diseases: a narrative review

T helper 9 (Th9) cells are a newly identified subset of effector T cells, characterized by their production of IL-9, a hallmark cytokine. Transcription factors such as PU.1 and IRF4 bind to the IL9 gene promoter and transactivate its expression. IL-9 and its associated transcription factors regulate...

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Bibliographic Details
Main Authors: Wang-Dong Xu, You-Yue Chen, Yun-Wei Li, Jing Yang, An-Fang Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1615611/full
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