Targeting Th9 cells in autoimmune diseases: a narrative review
T helper 9 (Th9) cells are a newly identified subset of effector T cells, characterized by their production of IL-9, a hallmark cytokine. Transcription factors such as PU.1 and IRF4 bind to the IL9 gene promoter and transactivate its expression. IL-9 and its associated transcription factors regulate...
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Main Authors: | Wang-Dong Xu, You-Yue Chen, Yun-Wei Li, Jing Yang, An-Fang Huang |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-07-01
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Series: | Frontiers in Immunology |
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Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1615611/full |
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