Mechanical cues orchestrate monocyte behavior in immune regulation and disease

Mechanical cues orchestrate monocyte behavior in immune regulation and disease

Monocytes, key mediators of innate immunity, exhibit remarkable sensitivity to mechanical cues such as extracellular matrix (ECM) stiffness, substrate rigidity, shear stress, compression, and hydrostatic pressure, which shape their activation, differentiation, and functional polarization. Monocytes...

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Bibliographic Details
Main Authors: Yifan Lin, Hardik Makkar, Shuchen Zhang, Bingling Chen, Chaoning Zhan, Kyle Vining
Format: Article
Language:English
Published: AIP Publishing LLC 2025-06-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0268234
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