Optimization of chlorpheniramine maleate (CPM) delivery by response surface methodology – four component modeling using various response times and concentrations of chitosan-alanine, glutaraldehyde and CPM
The aim of the current study was to investigate the effects of formulation variables on the release of drug and to optimize the formulation of chitosan-alanine beads loaded with chlorpheniramine maleate (CPM) for controlled release using response surface methodology (RSM). Drug loaded beads of chito...
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Format: | Article |
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Language: | English |
Published: |
Budapest University of Technology and Economics
2009-04-01
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Series: | eXPRESS Polymer Letters |
Subjects: | |
Online Access: | http://www.expresspolymlett.com/letolt.php?file=EPL-0000862&mi=cd |
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