PROSTATE CANCER WITH A HIGH BASELINE PSA LEVEL AFTER COMBINED TREATMENT

This article describes a rare clinical case of prostate cancer with a high baseline PSA level of 1407 hg/ml. In the course of diagnosis, hormonal and surgical treatment there was a successive dynamics of PSA decline: 07.08.2015–1407 ng/ ml, 14.09.2015–43,61ng/ml; 17.11.2015–0,326 ng/ml; 13.02.2016 (...

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Main Authors: A. T. Asratov, A. S. Kalpinskiy, I. A. Taraki, Yu. V. Samsonov, A. A. Kostin
Format: Article
Language:Russian
Published: QUASAR, LLC 2017-12-01
Series:Исследования и практика в медицине
Subjects:
Online Access:https://www.rpmj.ru/rpmj/article/view/228
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author A. T. Asratov
A. S. Kalpinskiy
I. A. Taraki
Yu. V. Samsonov
A. A. Kostin
author_facet A. T. Asratov
A. S. Kalpinskiy
I. A. Taraki
Yu. V. Samsonov
A. A. Kostin
author_sort A. T. Asratov
collection DOAJ
description This article describes a rare clinical case of prostate cancer with a high baseline PSA level of 1407 hg/ml. In the course of diagnosis, hormonal and surgical treatment there was a successive dynamics of PSA decline: 07.08.2015–1407 ng/ ml, 14.09.2015–43,61ng/ml; 17.11.2015–0,326 ng/ml; 13.02.2016 (end of hormone therapy) — 0,084 ng/ml. After the operation of radical prostatectomy with enlarged lymphadenectomy, on 20.04.2016 (with prolonged hormone therapy up to 9 monthes) gradual decrease of PSA level continued: 05.05.2016–0,008 ng/ml; 17.06.2016–0,008 ng/ml; 08.09.2016–0,039 ng/ml; 30.11.2016–0,002 ng/ml; 07.09.2017 (total PSA) — 0,008 ng/ml. In parallel, there was a consistent improvement in the clinical picture, up to the MRI data of 19.10.2017, when there were no significant neoplastic changes at the level of the study (in the projection of the prostatic bed).
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spelling doaj-art-fdfdb2dfbfb3424fbc75b2034d6c1a1c2025-08-04T14:04:03ZrusQUASAR, LLCИсследования и практика в медицине2410-18932017-12-014413314210.17709/2409-2231-2017-4-4-14178PROSTATE CANCER WITH A HIGH BASELINE PSA LEVEL AFTER COMBINED TREATMENTA. T. Asratov0A. S. Kalpinskiy1I. A. Taraki2Yu. V. Samsonov3A. A. Kostin4P. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Radiology Research Centre of the Ministry of Health of the Russian FederationP. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Radiology Research Centre of the Ministry of Health of the Russian FederationP. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Radiology Research Centre of the Ministry of Health of the Russian FederationP. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Radiology Research Centre of the Ministry of Health of the Russian FederationP. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Radiology Research Centre of the Ministry of Health of the Russian FederationThis article describes a rare clinical case of prostate cancer with a high baseline PSA level of 1407 hg/ml. In the course of diagnosis, hormonal and surgical treatment there was a successive dynamics of PSA decline: 07.08.2015–1407 ng/ ml, 14.09.2015–43,61ng/ml; 17.11.2015–0,326 ng/ml; 13.02.2016 (end of hormone therapy) — 0,084 ng/ml. After the operation of radical prostatectomy with enlarged lymphadenectomy, on 20.04.2016 (with prolonged hormone therapy up to 9 monthes) gradual decrease of PSA level continued: 05.05.2016–0,008 ng/ml; 17.06.2016–0,008 ng/ml; 08.09.2016–0,039 ng/ml; 30.11.2016–0,002 ng/ml; 07.09.2017 (total PSA) — 0,008 ng/ml. In parallel, there was a consistent improvement in the clinical picture, up to the MRI data of 19.10.2017, when there were no significant neoplastic changes at the level of the study (in the projection of the prostatic bed).https://www.rpmj.ru/rpmj/article/view/228prostate cancerdynamics of psa levelcombined treatment (hormonal and surgical)
spellingShingle A. T. Asratov
A. S. Kalpinskiy
I. A. Taraki
Yu. V. Samsonov
A. A. Kostin
PROSTATE CANCER WITH A HIGH BASELINE PSA LEVEL AFTER COMBINED TREATMENT
Исследования и практика в медицине
prostate cancer
dynamics of psa level
combined treatment (hormonal and surgical)
title PROSTATE CANCER WITH A HIGH BASELINE PSA LEVEL AFTER COMBINED TREATMENT
title_full PROSTATE CANCER WITH A HIGH BASELINE PSA LEVEL AFTER COMBINED TREATMENT
title_fullStr PROSTATE CANCER WITH A HIGH BASELINE PSA LEVEL AFTER COMBINED TREATMENT
title_full_unstemmed PROSTATE CANCER WITH A HIGH BASELINE PSA LEVEL AFTER COMBINED TREATMENT
title_short PROSTATE CANCER WITH A HIGH BASELINE PSA LEVEL AFTER COMBINED TREATMENT
title_sort prostate cancer with a high baseline psa level after combined treatment
topic prostate cancer
dynamics of psa level
combined treatment (hormonal and surgical)
url https://www.rpmj.ru/rpmj/article/view/228
work_keys_str_mv AT atasratov prostatecancerwithahighbaselinepsalevelaftercombinedtreatment
AT askalpinskiy prostatecancerwithahighbaselinepsalevelaftercombinedtreatment
AT iataraki prostatecancerwithahighbaselinepsalevelaftercombinedtreatment
AT yuvsamsonov prostatecancerwithahighbaselinepsalevelaftercombinedtreatment
AT aakostin prostatecancerwithahighbaselinepsalevelaftercombinedtreatment