Rationale and study protocol of the MAMELI Cohort study (Mapping the Methylation of repetitive elements to track the Exposome effects on health: the city of Legnano as a Living lab).

Rationale and study protocol of the MAMELI Cohort study (Mapping the Methylation of repetitive elements to track the Exposome effects on health: the city of Legnano as a Living lab).

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The concept of the exposome encompasses all the factors influencing human health throughout the life course. The exposome induces epigenetic changes, such as DNA methylation, which influence gene expression and impact overall health. Several recent studies have explored how repetitive elements (REs)...

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Main Authors: Valentina Bollati, Federica Rota, Laura Dioni, Chiara Favero, Simona Iodice, Marta Gallazzi, Andrea Spinazzè, Giacomo Fanti, Davide Campagnolo, Tiago Nardi, Davide Biganzoli, Eva Dariol, Rachele Matsagani, Mirjam Hoxha, Paola Monti, Benedetta Albetti, Letizia Tarantini, Davide Barbuto, Ester Luconi, Giuseppe Marano, Giacomo Biganzoli, Roberta Biciuffi, Patrizia Boracchi, Domenico M Cavallo, Pilar M Guerrieri, Fabio Mosca, Stefano Gustincich, Giovanni Sanesi, Luca Ferrari, Michele Carugno, Silvia Fustinoni, Angela Cecilia Pesatori, Luca Pandolfini, Michele Miragoli, Andrea Cattaneo, Elia Biganzoli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0326467
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