Antibiotic Resistance of Enterococci Isolated from Healthy Humans and Patients with Various Pathologies

High resistance of enterococci to the currently used antibacterials, such as tetracycline, ciprofloxacin and ampicillin was observed. Streptomycin, gentamicin and vancomycin showed the highest activity against the clinical isolates of Enterococcus spp. Streptomycin and gentamicin showed the highest...

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Main Authors: M. V. Sycheva, O. L. Kartashova, N. E. Shchepitova, Al. A. Safronov
Format: Article
Language:Russian
Published: LLC "Publishing House OKI" 2020-05-01
Series:Антибиотики и Химиотерапия
Subjects:
Online Access:https://www.antibiotics-chemotherapy.ru/jour/article/view/676
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author M. V. Sycheva
O. L. Kartashova
N. E. Shchepitova
Al. A. Safronov
author_facet M. V. Sycheva
O. L. Kartashova
N. E. Shchepitova
Al. A. Safronov
author_sort M. V. Sycheva
collection DOAJ
description High resistance of enterococci to the currently used antibacterials, such as tetracycline, ciprofloxacin and ampicillin was observed. Streptomycin, gentamicin and vancomycin showed the highest activity against the clinical isolates of Enterococcus spp. Streptomycin and gentamicin showed the highest activity against the intestinal enterococci. The PCR revealed the presence of the genetic determinants of resistance to aminoglycosides, glycopeptides and tetracycline in the isolates. The comparison of the results of the bacteriological and genetic tests provided detection of fecal and clinical isolates of Enterococcus spp. possessing the genes of resistance to aminoglycosides and glycopeptides, still without the finally developed significant clinical resistance to the above antibacterials.
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institution Matheson Library
issn 0235-2990
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publishDate 2020-05-01
publisher LLC "Publishing House OKI"
record_format Article
series Антибиотики и Химиотерапия
spelling doaj-art-fd3878dd8f5d4f76b4154f79ea6acd312025-08-03T13:04:47ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-05-01617-82732675Antibiotic Resistance of Enterococci Isolated from Healthy Humans and Patients with Various PathologiesM. V. Sycheva0O. L. Kartashova1N. E. Shchepitova2Al. A. Safronov3Institute of Cellular and Intracellular Symbiosis, Ural Branch of Russian Academy of Sciences; Orenburg State Agrarian UniversityInstitute of Cellular and Intracellular Symbiosis, Ural Branch of Russian Academy of SciencesOrenburg State Agrarian UniversityOrenburg State Medical University; Municipal Clinical Hospital No. 4High resistance of enterococci to the currently used antibacterials, such as tetracycline, ciprofloxacin and ampicillin was observed. Streptomycin, gentamicin and vancomycin showed the highest activity against the clinical isolates of Enterococcus spp. Streptomycin and gentamicin showed the highest activity against the intestinal enterococci. The PCR revealed the presence of the genetic determinants of resistance to aminoglycosides, glycopeptides and tetracycline in the isolates. The comparison of the results of the bacteriological and genetic tests provided detection of fecal and clinical isolates of Enterococcus spp. possessing the genes of resistance to aminoglycosides and glycopeptides, still without the finally developed significant clinical resistance to the above antibacterials.https://www.antibiotics-chemotherapy.ru/jour/article/view/676enterococcus sppenterococcus sppantibacterialsantibiotic resistance
spellingShingle M. V. Sycheva
O. L. Kartashova
N. E. Shchepitova
Al. A. Safronov
Antibiotic Resistance of Enterococci Isolated from Healthy Humans and Patients with Various Pathologies
Антибиотики и Химиотерапия
enterococcus spp
enterococcus spp
antibacterials
antibiotic resistance
title Antibiotic Resistance of Enterococci Isolated from Healthy Humans and Patients with Various Pathologies
title_full Antibiotic Resistance of Enterococci Isolated from Healthy Humans and Patients with Various Pathologies
title_fullStr Antibiotic Resistance of Enterococci Isolated from Healthy Humans and Patients with Various Pathologies
title_full_unstemmed Antibiotic Resistance of Enterococci Isolated from Healthy Humans and Patients with Various Pathologies
title_short Antibiotic Resistance of Enterococci Isolated from Healthy Humans and Patients with Various Pathologies
title_sort antibiotic resistance of enterococci isolated from healthy humans and patients with various pathologies
topic enterococcus spp
enterococcus spp
antibacterials
antibiotic resistance
url https://www.antibiotics-chemotherapy.ru/jour/article/view/676
work_keys_str_mv AT mvsycheva antibioticresistanceofenterococciisolatedfromhealthyhumansandpatientswithvariouspathologies
AT olkartashova antibioticresistanceofenterococciisolatedfromhealthyhumansandpatientswithvariouspathologies
AT neshchepitova antibioticresistanceofenterococciisolatedfromhealthyhumansandpatientswithvariouspathologies
AT alasafronov antibioticresistanceofenterococciisolatedfromhealthyhumansandpatientswithvariouspathologies