CYP3A4 isoenzyme phenotyping for personalisation of pharmacotherapy

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CYP3A4 isoenzyme phenotyping for personalisation of pharmacotherapy

The article reviews existing methods of determining CYP3A4 isoenzyme activity. The authors assess the significance of CYP3A4 activity determination and the applicability of these methods in clinical practice to adjust drugs doses and minimize risks of adverse reactions. The article demonstrates the...

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Bibliographic Details
Main Authors:	E. A. Egorenkov, V. V. Smirnov, V. N. Kuzina, S. P. Dementiev, G. V. Ramenskaya
Format:	Article
Language:	Russian
Published:	Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’) 2018-02-01
Series:	Регуляторные исследования и экспертиза лекарственных средств
Subjects:	цитохром p450 cyp3a4 фенотипирование персонализированная медицина рациональная фармакотерапия p450 cytochrome phenotyping personalized medicine rational pharmacotherapy
Online Access:	https://www.vedomostincesmp.ru/jour/article/view/113
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