Impact of the COVID-19 Pandemic on Pediatric Pneumonia Outcomes: A Five-Year Retrospective Cohort Study
Pavel Heinige,1 Lea Slováková,2 Jitka Vočková,2 Lan Ngoc Leová,3 Alice Tašková,4 Kateřina Kripnerová,5 Martin Prchlík,1 Karolína Doležalová2 1Department of Pediatric Intensive Care, Thomayer University Hospital, Prague, Czech Republic; 2Clinic of Paediatr...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2025-07-01
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| Series: | Infection and Drug Resistance |
| Subjects: | |
| Online Access: | https://www.dovepress.com/impact-of-the-covid-19-pandemic-on-pediatric-pneumonia-outcomes-a-five-peer-reviewed-fulltext-article-IDR |
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| Summary: | Pavel Heinige,1 Lea Slováková,2 Jitka Vo&ccaron;ková,2 Lan Ngoc Leová,3 Alice Tašková,4 Kate&rcaron;ina Kripnerová,5 Martin Prchlík,1 Karolína Dole&zcaron;alová2 1Department of Pediatric Intensive Care, Thomayer University Hospital, Prague, Czech Republic; 2Clinic of Paediatrics of the First Faculty of Medicine, Charles University, Thomayer University Hospital, Prague, Czech Republic; 3Department of Radiology, Thomayer University Hospital, Prague, Czech Republic; 4Clinic of Thoracic Surgery 3rd Faculty of Medicine, Charles University and Thomayer University Hospital, Prague, Czech Republic; 5Department of Clinical Microbiology, Thomayer University Hospital, Prague, Czech RepublicCorrespondence: Karolína Dole&zcaron;alová, Clinic of Paediatrics of the First Faculty of Medicine, Charles University, Thomayer University Hospital, Prague, Czech Republic, Email karolina.dolezalova@ftn.czBackground: Pneumonia remains a leading cause of pediatric morbidity globally, with Streptococcus pneumoniae (SP) as the primary bacterial pathogen. Despite vaccination programs and modern antibiotics, complicated cases requiring surgical intervention present ongoing challenges for healthcare providers. Recent clinical observations suggest an increase in complicated pneumonia cases requiring surgical intervention, particularly in the post-COVID-19 era. This trend warrants systematic investigation to optimize treatment protocols and surgical timing.Objective: Primary objectives: Examine epidemiological trends in pediatric pneumonia (2019– 2023) and evaluate surgical treatment outcomes. Secondary objectives: Analyze demographic and clinical characteristics, assess treatment response patterns and investigate factors associated with complicated disease courses.Methods: A retrospective, single-center study was conducted at Thomayer University Hospital, Prague, Czech Republic, analysing medical records of children diagnosed with pneumonia in years 2019– 2024. Data highly suggestive to Streptococcus pneumoniae were assessed for trends in incidence, clinical characteristics, treatment outcomes, surgical interventions, and antibiotic resistance. Statistical analysis using linear regression and Somers’ D statistic confirmed an increasing trend in total and complicated pneumonia cases in the years following the onset of the pandemic. Three figures depict severe cases.Results: We collected a total of 305 pediatric patients with community-acquired pneumonia (CAP). A total of 181 patients out of all CAP patients (59.3%) were suspected from pneumococcal aethiology. About 12.1% were identified as complicated. The statistical models showed significant increases over time (P < 0.05), with the complication rate rising by 0.143 per year (R² = 0.804) and interventions increasing by 0.062 per year (R² = 0.69).Conclusion: This study highlights a rising incidence of bacterial pneumonia, mainly pneumococcal, and its severe forms in children, particularly after the emergence of the pandemic. The findings underscore the need for a multidisciplinary approach and the role of minimally invasive surgical techniques in managing complex cases.&#x202FPlain Language Summary: Pneumonia is a common and serious lung infection in children. Pneumococcus is one of the main bacteria that causes it. Thanks to vaccines and antibiotics, many cases are mild and can be treated effectively. However, some children develop severe forms of pneumonia, which can lead to complications requiring surgery.Recent reports suggest that the number of complicated pneumonia cases has increased, especially after the COVID-19 pandemic. To understand this trend, we studied cases of pneumonia in children treated at Thomayer University Hospital in Prague between 2019 and 2024. We analyzed how often Pneumococcus was involved, how severe the cases were, and whether more children needed surgery over time.We found that out of 305 children with pneumonia, 181 (59.3%) were likely to have pneumococcal pneumonia. About 12% of these children developed severe complications. Our analysis showed a clear increase in the number of complicated cases and surgical interventions over time, especially after COVID-19. One particularly severe form, necrotizing pneumonia, which destroys lung tissue, was more common in recent years.These findings suggest that complicated bacterial pneumonia is becoming more frequent in children, and doctors may need to adjust their treatment strategies. Using less invasive surgical techniques and ensuring timely medical care could help improve outcomes for children with severe pneumonia.Keywords: pneumonia, Streptococcus pneumoniae, epidemiology, necrotising pneumonia with cavity formation, surgical management |
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| ISSN: | 1178-6973 |