Diverse Presentations of Extrauterine Leiomyomas in the Female Urogenital Tract: A Retrospective Series of 51 Cases

Background: Extrauterine leiomyomas (EULs) are rare benign smooth muscle tumors that arise outside the uterus, often leading to diagnostic challenges. Objective: To evaluate the clinical and pathological characteristics of EULs and their management in a tertiary care setting. Methods: This retrospec...

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Main Authors: Tanvi Jha, Arvind Ahuja, Anuj Chachra, Purnima Paliwal, Kamna Dutta
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-04-01
Series:Journal of Mid-Life Health
Subjects:
Online Access:https://journals.lww.com/10.4103/jmh.jmh_7_25
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author Tanvi Jha
Arvind Ahuja
Anuj Chachra
Purnima Paliwal
Kamna Dutta
author_facet Tanvi Jha
Arvind Ahuja
Anuj Chachra
Purnima Paliwal
Kamna Dutta
author_sort Tanvi Jha
collection DOAJ
description Background: Extrauterine leiomyomas (EULs) are rare benign smooth muscle tumors that arise outside the uterus, often leading to diagnostic challenges. Objective: To evaluate the clinical and pathological characteristics of EULs and their management in a tertiary care setting. Methods: This retrospective study reviewed 51 cases of EULs over a 5.5-year period. Data on demographics, clinical presentation, tumor location, histology, and treatment were analyzed. Results: The mean patient age was 41.6 years, with 41.2% aged 40–50 and 15.7% post-menopausal. Abnormal uterine bleeding (AUB) was the most common symptom (66.7%). Tumors were most frequently located in the cervix (72.5%), followed by the broad ligament (11.8%) and ovaries (7.8%). Histologically, EULs resembled uterine leiomyomas, showing spindle-shaped cells and low mitotic activity. Surgical excision was the primary treatment. Conclusion: EULs, though uncommon, should be considered in differential diagnoses of pelvic masses. Accurate histopathological evaluation is essential to avoid misdiagnosis and unnecessary intervention. This study enhances current understanding of EUL presentation and management.
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spelling doaj-art-fcc54c82e8434e28a78bd6ea3bcc5afa2025-07-05T15:57:20ZengWolters Kluwer Medknow PublicationsJournal of Mid-Life Health0976-78000976-78192025-04-0116214414710.4103/jmh.jmh_7_25Diverse Presentations of Extrauterine Leiomyomas in the Female Urogenital Tract: A Retrospective Series of 51 CasesTanvi JhaArvind AhujaAnuj ChachraPurnima PaliwalKamna DuttaBackground: Extrauterine leiomyomas (EULs) are rare benign smooth muscle tumors that arise outside the uterus, often leading to diagnostic challenges. Objective: To evaluate the clinical and pathological characteristics of EULs and their management in a tertiary care setting. Methods: This retrospective study reviewed 51 cases of EULs over a 5.5-year period. Data on demographics, clinical presentation, tumor location, histology, and treatment were analyzed. Results: The mean patient age was 41.6 years, with 41.2% aged 40–50 and 15.7% post-menopausal. Abnormal uterine bleeding (AUB) was the most common symptom (66.7%). Tumors were most frequently located in the cervix (72.5%), followed by the broad ligament (11.8%) and ovaries (7.8%). Histologically, EULs resembled uterine leiomyomas, showing spindle-shaped cells and low mitotic activity. Surgical excision was the primary treatment. Conclusion: EULs, though uncommon, should be considered in differential diagnoses of pelvic masses. Accurate histopathological evaluation is essential to avoid misdiagnosis and unnecessary intervention. This study enhances current understanding of EUL presentation and management.https://journals.lww.com/10.4103/jmh.jmh_7_25diverse presentationsextrauterine leiomyomasfemale genital tractunusual sites
spellingShingle Tanvi Jha
Arvind Ahuja
Anuj Chachra
Purnima Paliwal
Kamna Dutta
Diverse Presentations of Extrauterine Leiomyomas in the Female Urogenital Tract: A Retrospective Series of 51 Cases
Journal of Mid-Life Health
diverse presentations
extrauterine leiomyomas
female genital tract
unusual sites
title Diverse Presentations of Extrauterine Leiomyomas in the Female Urogenital Tract: A Retrospective Series of 51 Cases
title_full Diverse Presentations of Extrauterine Leiomyomas in the Female Urogenital Tract: A Retrospective Series of 51 Cases
title_fullStr Diverse Presentations of Extrauterine Leiomyomas in the Female Urogenital Tract: A Retrospective Series of 51 Cases
title_full_unstemmed Diverse Presentations of Extrauterine Leiomyomas in the Female Urogenital Tract: A Retrospective Series of 51 Cases
title_short Diverse Presentations of Extrauterine Leiomyomas in the Female Urogenital Tract: A Retrospective Series of 51 Cases
title_sort diverse presentations of extrauterine leiomyomas in the female urogenital tract a retrospective series of 51 cases
topic diverse presentations
extrauterine leiomyomas
female genital tract
unusual sites
url https://journals.lww.com/10.4103/jmh.jmh_7_25
work_keys_str_mv AT tanvijha diversepresentationsofextrauterineleiomyomasinthefemaleurogenitaltractaretrospectiveseriesof51cases
AT arvindahuja diversepresentationsofextrauterineleiomyomasinthefemaleurogenitaltractaretrospectiveseriesof51cases
AT anujchachra diversepresentationsofextrauterineleiomyomasinthefemaleurogenitaltractaretrospectiveseriesof51cases
AT purnimapaliwal diversepresentationsofextrauterineleiomyomasinthefemaleurogenitaltractaretrospectiveseriesof51cases
AT kamnadutta diversepresentationsofextrauterineleiomyomasinthefemaleurogenitaltractaretrospectiveseriesof51cases