Single-surgeon outcomes of open radical cystectomy for muscle-invasive bladder cancer: Experience from a tertiary center in Azerbaijan
Summary: Objective: Radical cystectomy is the standard treatment for muscle-invasive bladder cancer (MIBC). This study presents the first analysis of open radical cystectomy (ORC) outcomes in Azerbaijan, where robotic surgery is unavailable. Methods: We retrospectively analyzed 106 patients with no...
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Elsevier
2025-09-01
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| Series: | Surgery in Practice and Science |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666262025000257 |
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| author | Rashad Sholan Rufat Aliyev Seymur Karimov Jamal Musayev Anar Almazkhanli Rahman Ismayilov |
| author_facet | Rashad Sholan Rufat Aliyev Seymur Karimov Jamal Musayev Anar Almazkhanli Rahman Ismayilov |
| author_sort | Rashad Sholan |
| collection | DOAJ |
| description | Summary: Objective: Radical cystectomy is the standard treatment for muscle-invasive bladder cancer (MIBC). This study presents the first analysis of open radical cystectomy (ORC) outcomes in Azerbaijan, where robotic surgery is unavailable. Methods: We retrospectively analyzed 106 patients with non-metastatic MIBC who underwent ORC with bilateral pelvic lymph node dissection and Bricker ileal conduit reconstruction, performed by a single surgeon between 2014 and 2024. Demographic data, comorbidities, operative metrics (duration, blood loss), complications, length of stay, and follow-up data were analyzed. Results: The cohort's mean age was 64.2 years (72.6 % male), with common comorbidities including hypertension (33 %), diabetes (33 %), and coronary artery disease (24.5 %). The median operative time was 300 min and blood loss was 450 mL. Postoperative complications occurred in 9.4 %, primarily urinary tract infections. No intraoperative complications or in-hospital mortalities occurred. Longer hospital stays were associated with advanced age (p < 0.001), higher body mass index (p = 0.042), longer operative time (p < 0.001), and increased blood loss (p = 0.008). Of all patients, 58.5 % were followed for a median of 71.3 months with no observed recurrences. There were three non-cancer related deaths. Conclusion: This initial report from Azerbaijan demonstrates acceptable perioperative outcomes for ORC in MIBC, despite the absence of robotic surgery. Our findings emphasize optimizing surgical efficiency, comorbidity management, and strengthening follow-up to enhance patient outcomes in resource-limited settings. |
| format | Article |
| id | doaj-art-fbd44e9a3bfe40ceb4587a1ac0c09ac2 |
| institution | Matheson Library |
| issn | 2666-2620 |
| language | English |
| publishDate | 2025-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Surgery in Practice and Science |
| spelling | doaj-art-fbd44e9a3bfe40ceb4587a1ac0c09ac22025-07-11T04:31:48ZengElsevierSurgery in Practice and Science2666-26202025-09-0122100296Single-surgeon outcomes of open radical cystectomy for muscle-invasive bladder cancer: Experience from a tertiary center in AzerbaijanRashad Sholan0Rufat Aliyev1Seymur Karimov2Jamal Musayev3Anar Almazkhanli4Rahman Ismayilov5Scientific Research Center, State Security Service Military Hospital, Baku, Azerbaijan.; Scientific Research Center, Azerbaijan Medical University, Baku, Azerbaijan.; Correspondence author at. Scientific Research Center, State Security Service Military Hospital, Baku, Azerbaijan. Address: AZ1000, Baku city, Badamdar, Mektebli street, 1.Scientific Research Center, State Security Service Military Hospital, Baku, Azerbaijan.Department of Kidney Diseases and Organ Transplantation, State Security Service Military Hospital, Baku, Azerbaijan.Department of Pathology, Baku Pathology Center, Baku, AzerbaijanDepartment of Kidney Diseases and Organ Transplantation, State Security Service Military Hospital, Baku, Azerbaijan.Department of Kidney Diseases and Organ Transplantation, State Security Service Military Hospital, Baku, Azerbaijan.Summary: Objective: Radical cystectomy is the standard treatment for muscle-invasive bladder cancer (MIBC). This study presents the first analysis of open radical cystectomy (ORC) outcomes in Azerbaijan, where robotic surgery is unavailable. Methods: We retrospectively analyzed 106 patients with non-metastatic MIBC who underwent ORC with bilateral pelvic lymph node dissection and Bricker ileal conduit reconstruction, performed by a single surgeon between 2014 and 2024. Demographic data, comorbidities, operative metrics (duration, blood loss), complications, length of stay, and follow-up data were analyzed. Results: The cohort's mean age was 64.2 years (72.6 % male), with common comorbidities including hypertension (33 %), diabetes (33 %), and coronary artery disease (24.5 %). The median operative time was 300 min and blood loss was 450 mL. Postoperative complications occurred in 9.4 %, primarily urinary tract infections. No intraoperative complications or in-hospital mortalities occurred. Longer hospital stays were associated with advanced age (p < 0.001), higher body mass index (p = 0.042), longer operative time (p < 0.001), and increased blood loss (p = 0.008). Of all patients, 58.5 % were followed for a median of 71.3 months with no observed recurrences. There were three non-cancer related deaths. Conclusion: This initial report from Azerbaijan demonstrates acceptable perioperative outcomes for ORC in MIBC, despite the absence of robotic surgery. Our findings emphasize optimizing surgical efficiency, comorbidity management, and strengthening follow-up to enhance patient outcomes in resource-limited settings.http://www.sciencedirect.com/science/article/pii/S2666262025000257Radical cystectomyBladder cancerAzerbaijan |
| spellingShingle | Rashad Sholan Rufat Aliyev Seymur Karimov Jamal Musayev Anar Almazkhanli Rahman Ismayilov Single-surgeon outcomes of open radical cystectomy for muscle-invasive bladder cancer: Experience from a tertiary center in Azerbaijan Surgery in Practice and Science Radical cystectomy Bladder cancer Azerbaijan |
| title | Single-surgeon outcomes of open radical cystectomy for muscle-invasive bladder cancer: Experience from a tertiary center in Azerbaijan |
| title_full | Single-surgeon outcomes of open radical cystectomy for muscle-invasive bladder cancer: Experience from a tertiary center in Azerbaijan |
| title_fullStr | Single-surgeon outcomes of open radical cystectomy for muscle-invasive bladder cancer: Experience from a tertiary center in Azerbaijan |
| title_full_unstemmed | Single-surgeon outcomes of open radical cystectomy for muscle-invasive bladder cancer: Experience from a tertiary center in Azerbaijan |
| title_short | Single-surgeon outcomes of open radical cystectomy for muscle-invasive bladder cancer: Experience from a tertiary center in Azerbaijan |
| title_sort | single surgeon outcomes of open radical cystectomy for muscle invasive bladder cancer experience from a tertiary center in azerbaijan |
| topic | Radical cystectomy Bladder cancer Azerbaijan |
| url | http://www.sciencedirect.com/science/article/pii/S2666262025000257 |
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