Effectiveness of evidence-based nursing interventions in the management of patients with schizophrenia

BackgroundSchizophrenia is a severe psychiatric disorder characterized by persistent symptoms, functional impairment, and a high risk of relapse. Evidence-based nursing (EBN) is a patient-centered approach that applies clinical research to improve treatment adherence, reduce symptom severity, and su...

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Main Authors: Jiao Wen, Ming-Yan Li, Pan-Pan Song, Fei Teng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Psychiatry
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Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1610260/full
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author Jiao Wen
Ming-Yan Li
Pan-Pan Song
Fei Teng
author_facet Jiao Wen
Ming-Yan Li
Pan-Pan Song
Fei Teng
author_sort Jiao Wen
collection DOAJ
description BackgroundSchizophrenia is a severe psychiatric disorder characterized by persistent symptoms, functional impairment, and a high risk of relapse. Evidence-based nursing (EBN) is a patient-centered approach that applies clinical research to improve treatment adherence, reduce symptom severity, and support recovery. This study aimed to evaluate the effectiveness of EBN interventions in improving clinical and functional outcomes in patients with schizophrenia.Material and methodsThis retrospective study, conducted from January 2021 to December 2023, included 156 patients diagnosed with schizophrenia based on DSM-5 or ICD-10 criteria. Patients were divided into an observation group (n = 80) receiving EBN interventions and a control group (n = 76) receiving standard nursing care. EBN protocols included psychoeducation, behavioral rehabilitation, social skills training, family support, and medication supervision. Outcome measures included the Social Disability Screening Schedule (SDSS), Brief Psychiatric Rating Scale (BPRS), Modified Rehabilitation Status Scale (MRSS), and medication adherence rates. Statistical analyses were performed using SPSS 27.0, with a p-value of <0.05 indicating significance.ResultsBaseline characteristics were comparable between groups. After intervention, the observation group demonstrated significant improvements in SDSS and BPRS scores compared to the control group, reflecting enhanced social functionality and symptom management (p < 0.001). MRSS indicators, including dependency, social function, activity ability, and symptom behavior, also showed greater improvements in the observation group (p < 0.001). Medication adherence was significantly higher in the observation group, with higher complete adherence rates (40.0% vs. 19.7%) and fewer cases of non-adherence (25.0% vs. 47.4%, p = 0.003).ConclusionsEvidence-based nursing interventions improve social functionality, symptom management, recovery states, and medication adherence in schizophrenia, emphasizing their value in optimizing clinical outcomes.
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spelling doaj-art-fa83af9ee34e4f59b9767cfb3c99eac12025-08-01T05:31:58ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402025-08-011610.3389/fpsyt.2025.16102601610260Effectiveness of evidence-based nursing interventions in the management of patients with schizophreniaJiao Wen0Ming-Yan Li1Pan-Pan Song2Fei Teng3Outpatient Department, Shandong Mental Health Center, Jinan, Shandong, ChinaOutpatient Department, Chaoyang No. 7 Retired Cadre Recuperation Center, Beijing, ChinaDepartment of General Surgery, China-Japan Friendship Hospital, Beijing, ChinaDepartment of Psychiatry III, Shandong Mental Health Center, Jinan, Shandong, ChinaBackgroundSchizophrenia is a severe psychiatric disorder characterized by persistent symptoms, functional impairment, and a high risk of relapse. Evidence-based nursing (EBN) is a patient-centered approach that applies clinical research to improve treatment adherence, reduce symptom severity, and support recovery. This study aimed to evaluate the effectiveness of EBN interventions in improving clinical and functional outcomes in patients with schizophrenia.Material and methodsThis retrospective study, conducted from January 2021 to December 2023, included 156 patients diagnosed with schizophrenia based on DSM-5 or ICD-10 criteria. Patients were divided into an observation group (n = 80) receiving EBN interventions and a control group (n = 76) receiving standard nursing care. EBN protocols included psychoeducation, behavioral rehabilitation, social skills training, family support, and medication supervision. Outcome measures included the Social Disability Screening Schedule (SDSS), Brief Psychiatric Rating Scale (BPRS), Modified Rehabilitation Status Scale (MRSS), and medication adherence rates. Statistical analyses were performed using SPSS 27.0, with a p-value of <0.05 indicating significance.ResultsBaseline characteristics were comparable between groups. After intervention, the observation group demonstrated significant improvements in SDSS and BPRS scores compared to the control group, reflecting enhanced social functionality and symptom management (p < 0.001). MRSS indicators, including dependency, social function, activity ability, and symptom behavior, also showed greater improvements in the observation group (p < 0.001). Medication adherence was significantly higher in the observation group, with higher complete adherence rates (40.0% vs. 19.7%) and fewer cases of non-adherence (25.0% vs. 47.4%, p = 0.003).ConclusionsEvidence-based nursing interventions improve social functionality, symptom management, recovery states, and medication adherence in schizophrenia, emphasizing their value in optimizing clinical outcomes.https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1610260/fullschizophreniaevidence-based nursingsocial functionalitypsychiatric symptomsmedication adherence
spellingShingle Jiao Wen
Ming-Yan Li
Pan-Pan Song
Fei Teng
Effectiveness of evidence-based nursing interventions in the management of patients with schizophrenia
Frontiers in Psychiatry
schizophrenia
evidence-based nursing
social functionality
psychiatric symptoms
medication adherence
title Effectiveness of evidence-based nursing interventions in the management of patients with schizophrenia
title_full Effectiveness of evidence-based nursing interventions in the management of patients with schizophrenia
title_fullStr Effectiveness of evidence-based nursing interventions in the management of patients with schizophrenia
title_full_unstemmed Effectiveness of evidence-based nursing interventions in the management of patients with schizophrenia
title_short Effectiveness of evidence-based nursing interventions in the management of patients with schizophrenia
title_sort effectiveness of evidence based nursing interventions in the management of patients with schizophrenia
topic schizophrenia
evidence-based nursing
social functionality
psychiatric symptoms
medication adherence
url https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1610260/full
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