A case of acute abdomen caused by visceral disseminated varicella-zoster virus infection causes diagnostic challenges during the course of systemic lupus erythematosus

Visceral disseminated varicella-zoster virus (VD-VZV) infection, resulting from primary infection by, or reactivation of, VZV, is a rare and severe complication in immunosuppressed patients. Because VD-VZV often develops alongside acute abdominal pain, which precedes appearance of the skin rash, dia...

Full description

Saved in:
Bibliographic Details
Main Authors: Koki Matsushita, Yu Nagayoshi, Ryosuke Yamamura, Keishi Nakamura, Yutaka Kakizoe, Yuichiro Izumi, Masataka Adachi, Masashi Mukoyama, Hideki Yokoi
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:IDCases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214250925001738
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Visceral disseminated varicella-zoster virus (VD-VZV) infection, resulting from primary infection by, or reactivation of, VZV, is a rare and severe complication in immunosuppressed patients. Because VD-VZV often develops alongside acute abdominal pain, which precedes appearance of the skin rash, diagnosis is difficult. Here, we report a case of 48-year-old woman who presented with acute abdomen, leading to a diagnosis of VD-VZV infection. The patient developed systemic lupus erythematosus 4 months earlier, and had been treated with immunosuppressants. The patient was treated successfully with a 7-day course of intravenous acyclovir. VD-VZV infection should be considered as a differential diagnosis in immunosuppressed patients with acute abdomen. Early diagnosis and prompt treatment with antivirals are crucial for improved patient outcomes.
ISSN:2214-2509