MOLECULAR GENETIC MARKERS AS PREDICTORS OF TUMOR RESPONSE TO NEOADJUVANT CHEMOTHERAPY FOR RECTAL CANCER
The review presents the mechanisms involved in the biological behavior of rectal cancer cells. The tumor response to neoadjuvant chemoradiotherapy was evaluated. The characteristics of proliferative activity, apoptosis, cell adhesion, and migration of rectal cancer cells influenced by chemotherapy w...
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| Format: | Article |
| Language: | Russian |
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Russian Academy of Sciences, Tomsk National Research Medical Center
2016-11-01
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| Series: | Сибирский онкологический журнал |
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| Online Access: | https://www.siboncoj.ru/jour/article/view/408 |
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| author | S. R. Altybaev S. G. Afanasyev M. V. Zavyalova I. V. Stepanov D. A. Sorokin |
| author_facet | S. R. Altybaev S. G. Afanasyev M. V. Zavyalova I. V. Stepanov D. A. Sorokin |
| author_sort | S. R. Altybaev |
| collection | DOAJ |
| description | The review presents the mechanisms involved in the biological behavior of rectal cancer cells. The tumor response to neoadjuvant chemoradiotherapy was evaluated. The characteristics of proliferative activity, apoptosis, cell adhesion, and migration of rectal cancer cells influenced by chemotherapy were described. The relationship between molecular genetic markers and prediction of response to chemoradiation in rectal cancer was shown. |
| format | Article |
| id | doaj-art-f935f11b79cf4802bb4b63e2cd6ebbf4 |
| institution | Matheson Library |
| issn | 1814-4861 2312-3168 |
| language | Russian |
| publishDate | 2016-11-01 |
| publisher | Russian Academy of Sciences, Tomsk National Research Medical Center |
| record_format | Article |
| series | Сибирский онкологический журнал |
| spelling | doaj-art-f935f11b79cf4802bb4b63e2cd6ebbf42025-08-04T10:33:37ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682016-11-01155657210.21294/1814-4861-2016-15-5-65-72377MOLECULAR GENETIC MARKERS AS PREDICTORS OF TUMOR RESPONSE TO NEOADJUVANT CHEMOTHERAPY FOR RECTAL CANCERS. R. Altybaev0S. G. Afanasyev1M. V. Zavyalova2I. V. Stepanov3D. A. Sorokin4Siberian State Medical University, Russia, Tomsk 2, Moskovsky Tract, 634009-Tomsk, RussiaCancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Russia, TomskSiberian State Medical University, Russia, Tomsk 2, Moskovsky Tract, 634009-Tomsk, Russia Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Russia, TomskSiberian State Medical University, Russia, Tomsk 2, Moskovsky Tract, 634009-Tomsk, Russia Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Russia, TomskSiberian State Medical University, Russia, Tomsk 2, Moskovsky Tract, 634009-Tomsk, RussiaThe review presents the mechanisms involved in the biological behavior of rectal cancer cells. The tumor response to neoadjuvant chemoradiotherapy was evaluated. The characteristics of proliferative activity, apoptosis, cell adhesion, and migration of rectal cancer cells influenced by chemotherapy were described. The relationship between molecular genetic markers and prediction of response to chemoradiation in rectal cancer was shown.https://www.siboncoj.ru/jour/article/view/408rectal cancerneoadjuvant chemoradiationtumor responseimmunohistochemistrygenetic markers |
| spellingShingle | S. R. Altybaev S. G. Afanasyev M. V. Zavyalova I. V. Stepanov D. A. Sorokin MOLECULAR GENETIC MARKERS AS PREDICTORS OF TUMOR RESPONSE TO NEOADJUVANT CHEMOTHERAPY FOR RECTAL CANCER Сибирский онкологический журнал rectal cancer neoadjuvant chemoradiation tumor response immunohistochemistry genetic markers |
| title | MOLECULAR GENETIC MARKERS AS PREDICTORS OF TUMOR RESPONSE TO NEOADJUVANT CHEMOTHERAPY FOR RECTAL CANCER |
| title_full | MOLECULAR GENETIC MARKERS AS PREDICTORS OF TUMOR RESPONSE TO NEOADJUVANT CHEMOTHERAPY FOR RECTAL CANCER |
| title_fullStr | MOLECULAR GENETIC MARKERS AS PREDICTORS OF TUMOR RESPONSE TO NEOADJUVANT CHEMOTHERAPY FOR RECTAL CANCER |
| title_full_unstemmed | MOLECULAR GENETIC MARKERS AS PREDICTORS OF TUMOR RESPONSE TO NEOADJUVANT CHEMOTHERAPY FOR RECTAL CANCER |
| title_short | MOLECULAR GENETIC MARKERS AS PREDICTORS OF TUMOR RESPONSE TO NEOADJUVANT CHEMOTHERAPY FOR RECTAL CANCER |
| title_sort | molecular genetic markers as predictors of tumor response to neoadjuvant chemotherapy for rectal cancer |
| topic | rectal cancer neoadjuvant chemoradiation tumor response immunohistochemistry genetic markers |
| url | https://www.siboncoj.ru/jour/article/view/408 |
| work_keys_str_mv | AT sraltybaev moleculargeneticmarkersaspredictorsoftumorresponsetoneoadjuvantchemotherapyforrectalcancer AT sgafanasyev moleculargeneticmarkersaspredictorsoftumorresponsetoneoadjuvantchemotherapyforrectalcancer AT mvzavyalova moleculargeneticmarkersaspredictorsoftumorresponsetoneoadjuvantchemotherapyforrectalcancer AT ivstepanov moleculargeneticmarkersaspredictorsoftumorresponsetoneoadjuvantchemotherapyforrectalcancer AT dasorokin moleculargeneticmarkersaspredictorsoftumorresponsetoneoadjuvantchemotherapyforrectalcancer |