Loss of factor VIII in zebrafish rebalances antithrombin deficiency but has a limited bleeding diathesis
Abstract: Deficiencies in coagulation factor VIII (FVIII, F8) result in the bleeding disorder hemophilia A. An emerging novel therapeutic strategy for bleeding disorders is to enhance hemostasis by limiting natural anticoagulants, such as antithrombin (AT3). To study pro/anticoagulant hemostatic bal...
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Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-07-01
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Series: | Blood Advances |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2473952925001600 |
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