The Role of Prion Protein in Reelin/Dab1 Signaling: Implications for Neurodegeneration

The Role of Prion Protein in Reelin/Dab1 Signaling: Implications for Neurodegeneration

The cellular prion protein (PrP<sup>C</sup>) is studied in prion diseases, where its misfolded isoform (PrP<sup>Sc</sup>) leads to neurodegeneration. PrP<sup>C</sup> has also been implicated in several physiological functions. The protein is abundant in the nervou...

Full description

Saved in:
Bibliographic Details
Main Authors: Irene Giulia Rolle, Anna Burato, Merve Begüm Bacınoğlu, Fabio Moda, Giuseppe Legname
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Viruses
Subjects:
prion protein
Reelin
cleavage
Dab1
neurodegeneration
Online Access:https://www.mdpi.com/1999-4915/17/7/928
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items