Variable Relative Biological Effectiveness of Protons in the Rat Spinal Cord: Measurements and Comparison With Model Calculations

Purpose: To determine the relative biological effectiveness (RBE) in the rat spinal cord after 6 fractions of protons as a function of linear energy transfer (LET) and dose. Methods and Materials: The rat spinal cord was irradiated at 4 different positions of a 6 cm spread-out Bragg peak using 6 fra...

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Main Authors: Christin Glowa, PhD, Maria Saager, PhD, Lisa Hintz, MSc, Rosemarie Euler-Lange, BSc, Peter Peschke, PhD, Stephan Brons, PhD, Kaya Hilt, MSc, Thomas Friedrich, PhD, Michael Scholz, PhD, Hans Liew, PhD, Andrea Mairani, PhD, Christian P. Karger, PhD
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S245210942500096X
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