Radioactivity distribution in the blood and urine of patients receiving systemic therapy with a <sup>177</sup>Lu radiopharmaceutical and local (intra-articular) therapy with a <sup>188</sup>Re radiopharmaceutical

Radioactivity distribution in the blood and urine of patients receiving systemic therapy with a <sup>177</sup>Lu radiopharmaceutical and local (intra-articular) therapy with a <sup>188</sup>Re radiopharmaceutical

Pharmacokinetic parameters are important for calculating the absorbed dose; they also provide an indirect measure of the in vivo stability of a radiopharmaceutical. The aim of the study was to determine the excretion rate of the activity of 177Lu-DOTA-PSMA-617 and MCA 5–10 microns, 188Re, from the b...

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Bibliographic Details
Main Authors: E. D. Stepchenkova, V. K. Tishchenko, O. P. Vlasova, V. M. Petriev, N. S. Legkodimova, V. V. Krylov, A. V. Fedorova, E. A. Kuzenkova, A. A. Ostroukhoff, P. V. Shegai
Format: Article
Language:Russian
Published: Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’) 2022-12-01
Series:Регуляторные исследования и экспертиза лекарственных средств
Subjects:
radiopharmaceutical
radiometric analysis
radionuclide
<sup>177</sup>lu
<sup>188</sup>re
radiotherapy
pharmacokinetics
Online Access:https://www.vedomostincesmp.ru/jour/article/view/503
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