Diffuse midline glioma of the brainstem: genetic features, complications and treatment prospects
Diffuse midline glioma of the brain is a rare but very aggressive and resistant glial tumor. This pathology is characterized by impossibility of radical surgical treatment, radioresistance, resistance to drug treatment, high morbidity in children, low quality of life of the patients, frequent compli...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | Russian |
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ABV-press
2024-06-01
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| Series: | Опухоли головы и шеи |
| Subjects: | |
| Online Access: | https://ogsh.abvpress.ru/jour/article/view/968 |
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| author | A. M. Kryanev I. D. Rozanov S. S. Lebedev D. N. Grekov K. S. Titov T. A. Yakusheva M. Kh. Salpagarov |
| author_facet | A. M. Kryanev I. D. Rozanov S. S. Lebedev D. N. Grekov K. S. Titov T. A. Yakusheva M. Kh. Salpagarov |
| author_sort | A. M. Kryanev |
| collection | DOAJ |
| description | Diffuse midline glioma of the brain is a rare but very aggressive and resistant glial tumor. This pathology is characterized by impossibility of radical surgical treatment, radioresistance, resistance to drug treatment, high morbidity in children, low quality of life of the patients, frequent complications in the form of neurologic deficit, and unfavorable prognosis. The absence of effective treatment scheme for diffuse midline glioma requires identification of other methods (oncolytic virus therapy, immunotherapy) but there is not enough data on this topic leading to the necessity of its further investigation. |
| format | Article |
| id | doaj-art-f74aac19a27c4eceab442f1cfc1abc5f |
| institution | Matheson Library |
| issn | 2222-1468 2411-4634 |
| language | Russian |
| publishDate | 2024-06-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Опухоли головы и шеи |
| spelling | doaj-art-f74aac19a27c4eceab442f1cfc1abc5f2025-08-04T14:05:35ZrusABV-pressОпухоли головы и шеи2222-14682411-46342024-06-01141495510.17650/2222-1468-2024-14-1-49-55585Diffuse midline glioma of the brainstem: genetic features, complications and treatment prospectsA. M. Kryanev0I. D. Rozanov1S. S. Lebedev2D. N. Grekov3K. S. Titov4T. A. Yakusheva5M. Kh. Salpagarov6S.P. Botkin City Clinical Hospital, Moscow Healthcare DepartmentS.P. Botkin City Clinical Hospital, Moscow Healthcare DepartmentS.P. Botkin City Clinical Hospital, Moscow Healthcare Department; Russian Medical Academy of Continuing Professional Education, Ministry of Health of RussiaS.P. Botkin City Clinical Hospital, Moscow Healthcare Department; Russian Medical Academy of Continuing Professional Education, Ministry of Health of RussiaS.P. Botkin City Clinical Hospital, Moscow Healthcare Department; Peoples' Friendship University of RussiaS.P. Botkin City Clinical Hospital, Moscow Healthcare Department; Peoples' Friendship University of RussiaS.P. Botkin City Clinical Hospital, Moscow Healthcare DepartmentDiffuse midline glioma of the brain is a rare but very aggressive and resistant glial tumor. This pathology is characterized by impossibility of radical surgical treatment, radioresistance, resistance to drug treatment, high morbidity in children, low quality of life of the patients, frequent complications in the form of neurologic deficit, and unfavorable prognosis. The absence of effective treatment scheme for diffuse midline glioma requires identification of other methods (oncolytic virus therapy, immunotherapy) but there is not enough data on this topic leading to the necessity of its further investigation.https://ogsh.abvpress.ru/jour/article/view/968gliomadiffuse gliomapediatric gliomabrainstem gliomapontine gliomamidbrain glioma |
| spellingShingle | A. M. Kryanev I. D. Rozanov S. S. Lebedev D. N. Grekov K. S. Titov T. A. Yakusheva M. Kh. Salpagarov Diffuse midline glioma of the brainstem: genetic features, complications and treatment prospects Опухоли головы и шеи glioma diffuse glioma pediatric glioma brainstem glioma pontine glioma midbrain glioma |
| title | Diffuse midline glioma of the brainstem: genetic features, complications and treatment prospects |
| title_full | Diffuse midline glioma of the brainstem: genetic features, complications and treatment prospects |
| title_fullStr | Diffuse midline glioma of the brainstem: genetic features, complications and treatment prospects |
| title_full_unstemmed | Diffuse midline glioma of the brainstem: genetic features, complications and treatment prospects |
| title_short | Diffuse midline glioma of the brainstem: genetic features, complications and treatment prospects |
| title_sort | diffuse midline glioma of the brainstem genetic features complications and treatment prospects |
| topic | glioma diffuse glioma pediatric glioma brainstem glioma pontine glioma midbrain glioma |
| url | https://ogsh.abvpress.ru/jour/article/view/968 |
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