A Multiscale Quantitative Systems Pharmacology Model for the Development and Optimization of mRNA Vaccines

A Multiscale Quantitative Systems Pharmacology Model for the Development and Optimization of mRNA Vaccines

ABSTRACT The unprecedented effort to cope with the COVID‐19 pandemic has unlocked the potential of mRNA vaccines as a powerful technology, set to become increasingly pervasive in the years to come. As in other areas of drug development, mathematical modeling is a pivotal tool to support and expedite...

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Main Authors: Lorenzo Dasti, Stefano Giampiccolo, Elisa Pettinà, Giada Fiandaca, Natascia Zangani, Lorena Leonardelli, Fabio De Lima Hedayioglu, Elio Campanile, Luca Marchetti
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.70041
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