Recurrent adenoid cystic carcinoma of the vulva: A case report of salvage stereotactic ablative radiotherapy to the pudendal nerve
Adenoid cystic carcinoma (ACC) is an indolent malignancy that frequently recurs and particularly involves surrounding nerves which complicates management. ACC is mostly reported in the head-and-neck, but can also arise in the pelvis where treatment strategies are less established due to its rarity....
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| Language: | English |
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Elsevier
2025-10-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043325006144 |
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| author | Hanya Irfan, MBBS, BSc Yusuf Ben-Tarifite, BMBCh, BA Rana Mahmood, MBBS |
| author_facet | Hanya Irfan, MBBS, BSc Yusuf Ben-Tarifite, BMBCh, BA Rana Mahmood, MBBS |
| author_sort | Hanya Irfan, MBBS, BSc |
| collection | DOAJ |
| description | Adenoid cystic carcinoma (ACC) is an indolent malignancy that frequently recurs and particularly involves surrounding nerves which complicates management. ACC is mostly reported in the head-and-neck, but can also arise in the pelvis where treatment strategies are less established due to its rarity. In this case report a 44-year-old patient with previously treated vulval ACC presented with an isolated recurrence along the dorsal branch of the pudendal nerve. The pudendal nerve was successfully treated with salvage stereotactic ablative radiotherapy (SABR), with no evidence of active disease at 1-year follow-up. There is a potential role for SABR as an effective treatment for recurrent ACC with perineural spread, particularly when surgical options are limited. This case highlights the necessity of individualized treatment planning in rare anatomical presentations of ACC, with consideration for balancing oncological control with aim to preserve function. This report contributes to the limited literature on vulvar ACC and supports the integration of adjuvant radiotherapy into the multidisciplinary management. |
| format | Article |
| id | doaj-art-f6bf7195b2214c84a8b0f24d8b1a8dd5 |
| institution | Matheson Library |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-f6bf7195b2214c84a8b0f24d8b1a8dd52025-07-27T04:55:31ZengElsevierRadiology Case Reports1930-04332025-10-01201051485155Recurrent adenoid cystic carcinoma of the vulva: A case report of salvage stereotactic ablative radiotherapy to the pudendal nerveHanya Irfan, MBBS, BSc0Yusuf Ben-Tarifite, BMBCh, BA1Rana Mahmood, MBBS2Whittington Hospital Trust, Magdala Avenue, London, N19 5NF, England; Corresponding author.Oxford University Hospitals Trust, Headley Way, Headington, Oxford, OX3 9DU, EnglandMediclinic City Hospital, Dubai Healthcare City, Bldg 37-26th St, Umm Hurair 2, Dubai, United Arab EmiratesAdenoid cystic carcinoma (ACC) is an indolent malignancy that frequently recurs and particularly involves surrounding nerves which complicates management. ACC is mostly reported in the head-and-neck, but can also arise in the pelvis where treatment strategies are less established due to its rarity. In this case report a 44-year-old patient with previously treated vulval ACC presented with an isolated recurrence along the dorsal branch of the pudendal nerve. The pudendal nerve was successfully treated with salvage stereotactic ablative radiotherapy (SABR), with no evidence of active disease at 1-year follow-up. There is a potential role for SABR as an effective treatment for recurrent ACC with perineural spread, particularly when surgical options are limited. This case highlights the necessity of individualized treatment planning in rare anatomical presentations of ACC, with consideration for balancing oncological control with aim to preserve function. This report contributes to the limited literature on vulvar ACC and supports the integration of adjuvant radiotherapy into the multidisciplinary management.http://www.sciencedirect.com/science/article/pii/S1930043325006144Adenoid cystic carcinomaBartholin’s glandsCarcinomaStereotactic ablative radiotherapyVulval cancer, Gynecological-oncology |
| spellingShingle | Hanya Irfan, MBBS, BSc Yusuf Ben-Tarifite, BMBCh, BA Rana Mahmood, MBBS Recurrent adenoid cystic carcinoma of the vulva: A case report of salvage stereotactic ablative radiotherapy to the pudendal nerve Radiology Case Reports Adenoid cystic carcinoma Bartholin’s glands Carcinoma Stereotactic ablative radiotherapy Vulval cancer, Gynecological-oncology |
| title | Recurrent adenoid cystic carcinoma of the vulva: A case report of salvage stereotactic ablative radiotherapy to the pudendal nerve |
| title_full | Recurrent adenoid cystic carcinoma of the vulva: A case report of salvage stereotactic ablative radiotherapy to the pudendal nerve |
| title_fullStr | Recurrent adenoid cystic carcinoma of the vulva: A case report of salvage stereotactic ablative radiotherapy to the pudendal nerve |
| title_full_unstemmed | Recurrent adenoid cystic carcinoma of the vulva: A case report of salvage stereotactic ablative radiotherapy to the pudendal nerve |
| title_short | Recurrent adenoid cystic carcinoma of the vulva: A case report of salvage stereotactic ablative radiotherapy to the pudendal nerve |
| title_sort | recurrent adenoid cystic carcinoma of the vulva a case report of salvage stereotactic ablative radiotherapy to the pudendal nerve |
| topic | Adenoid cystic carcinoma Bartholin’s glands Carcinoma Stereotactic ablative radiotherapy Vulval cancer, Gynecological-oncology |
| url | http://www.sciencedirect.com/science/article/pii/S1930043325006144 |
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