Differences in the pharmacokinetics of ibuprofen in monoand multi-component drugs

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Differences in the pharmacokinetics of ibuprofen in monoand multi-component drugs

The article reports the results of the study which investigated the pharmacokinetics of mono- and multi-component ibuprofen-containing drugs following single oral administration to healthy volunteers. Plasma concentration of ibuprofen was determined by HPLC with spectrophotometric detection. The mai...

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Bibliographic Details
Main Authors:	L. M. Krasnykh, V. V. Smirnov, G. F. Vasilenko, O. A. Goroshko, E. A. Egorenkov, V. I. Zozina
Format:	Article
Language:	Russian
Published:	Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’) 2018-02-01
Series:	Регуляторные исследования и экспертиза лекарственных средств
Subjects:	ибупрофен нестероидные противовоспалительные средства высокоэффективная жидкостная хроматография фармакокинетика монопрепарат комбинированный препарат ibuprofen nonsteroidal anti-inflammatory drugs high performance liquid chromatography pharmacokinetics monocomponent drug combination drug
Online Access:	https://www.vedomostincesmp.ru/jour/article/view/129
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