An engineered recombinant protein containing three structural domains in SARS-CoV-2 S2 protein has potential to act as a pan-human coronavirus entry inhibitor or vaccine antigen
The threat to global health caused by three highly pathogenic human coronaviruses (HCoV), SARS-CoV-2, MERS-CoV and SARS-CoV, calls for the development of pan-HCoV therapeutics and vaccines. This study reports the design and engineering of a recombinant protein designated HR1LS. It contains three lin...
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Main Authors: | Xinling Wang, Lujia Sun, Zezhong Liu, Lixiao Xing, Yun Zhu, Wei Xu, Shuai Xia, Lu Lu, Shibo Jiang |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2023-12-01
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Series: | Emerging Microbes and Infections |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/22221751.2023.2244084 |
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