Regulatory roles of three-dimensional structures of chromatin domains
Abstract Background Transcriptional enhancers usually, but not always, regulate genes within the same topologically associating domain (TAD). We hypothesize that this incomplete insulation is partially due to three-dimensional structures of corresponding chromatin domains in individual cells: wherea...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-06-01
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| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-025-03659-7 |
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