Role of the chaperonin TCP-1 ring complex in protein aggregation and neurodegeneration
The chaperonin TCP-1 ring complex (TRiC), also known as chaperonin-containing TCP-1 (CCT) complex, plays a crucial role in protein folding and quality control within the cell. Comprising eight distinct subunits (CCT1 - CCT8), TRiC assists in the folding of a wide range of client proteins, ensuring t...
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Main Authors: | Vanlalrinchhani Varte, Diego E. Rincon-Limas |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-07-01
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Series: | Frontiers in Molecular Neuroscience |
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Online Access: | https://www.frontiersin.org/articles/10.3389/fnmol.2025.1617771/full |
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