Physiologic effects of different hemodynamic patterns of LVAD
Left ventricular assist device (LVAD) is an important treatment for patients with end-stage heart failure, which essentially replaces the left ventricle's pumping action to improve peripheral circulation. Its hemodynamic pattern (pulsatile vs. continuous flow) has been a popular research topic...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2025.1645705/full |
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| _version_ | 1839582600074625024 |
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| author | Jiahao Mao Zhen Gao Wenyuan Yu Yang Yu |
| author_facet | Jiahao Mao Zhen Gao Wenyuan Yu Yang Yu |
| author_sort | Jiahao Mao |
| collection | DOAJ |
| description | Left ventricular assist device (LVAD) is an important treatment for patients with end-stage heart failure, which essentially replaces the left ventricle's pumping action to improve peripheral circulation. Its hemodynamic pattern (pulsatile vs. continuous flow) has been a popular research topic in the field. Because of its dependability and endurance, the continuous flow LVAD (CFVAD), as opposed to the first generation of pulsatile flow LVAD (PFVAD), has gained popularity as a mechanical support device in clinical practice in recent years. Many of the complications that arise with CFVAD application are thought to be related to reduced pulsatility. This article provides a review of the physiologic effects of different hemodynamic patterns on the circulatory system and the difference in outcomes of PFVAD vs. CFVAD. |
| format | Article |
| id | doaj-art-f45e8f39c7d54bd78e25e0c4f2597a03 |
| institution | Matheson Library |
| issn | 2297-055X |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj-art-f45e8f39c7d54bd78e25e0c4f2597a032025-08-04T05:26:08ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2025-08-011210.3389/fcvm.2025.16457051645705Physiologic effects of different hemodynamic patterns of LVADJiahao MaoZhen GaoWenyuan YuYang YuLeft ventricular assist device (LVAD) is an important treatment for patients with end-stage heart failure, which essentially replaces the left ventricle's pumping action to improve peripheral circulation. Its hemodynamic pattern (pulsatile vs. continuous flow) has been a popular research topic in the field. Because of its dependability and endurance, the continuous flow LVAD (CFVAD), as opposed to the first generation of pulsatile flow LVAD (PFVAD), has gained popularity as a mechanical support device in clinical practice in recent years. Many of the complications that arise with CFVAD application are thought to be related to reduced pulsatility. This article provides a review of the physiologic effects of different hemodynamic patterns on the circulatory system and the difference in outcomes of PFVAD vs. CFVAD.https://www.frontiersin.org/articles/10.3389/fcvm.2025.1645705/fullpulsatile flowcontinuous flowleft ventricular assist device (LVAD)heart failurepulsatility |
| spellingShingle | Jiahao Mao Zhen Gao Wenyuan Yu Yang Yu Physiologic effects of different hemodynamic patterns of LVAD Frontiers in Cardiovascular Medicine pulsatile flow continuous flow left ventricular assist device (LVAD) heart failure pulsatility |
| title | Physiologic effects of different hemodynamic patterns of LVAD |
| title_full | Physiologic effects of different hemodynamic patterns of LVAD |
| title_fullStr | Physiologic effects of different hemodynamic patterns of LVAD |
| title_full_unstemmed | Physiologic effects of different hemodynamic patterns of LVAD |
| title_short | Physiologic effects of different hemodynamic patterns of LVAD |
| title_sort | physiologic effects of different hemodynamic patterns of lvad |
| topic | pulsatile flow continuous flow left ventricular assist device (LVAD) heart failure pulsatility |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2025.1645705/full |
| work_keys_str_mv | AT jiahaomao physiologiceffectsofdifferenthemodynamicpatternsoflvad AT zhengao physiologiceffectsofdifferenthemodynamicpatternsoflvad AT wenyuanyu physiologiceffectsofdifferenthemodynamicpatternsoflvad AT yangyu physiologiceffectsofdifferenthemodynamicpatternsoflvad |