Tight junctional protein family, Claudins in cancer and cancer metastasis

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Tight junctional protein family, Claudins in cancer and cancer metastasis

Claudin (CLDN) family proteins are key components of tight junctions in epithelial and endothelial cells, crucial for controlling paracellular permeability and cell-cell adhesion. Aberrant CLDNS expression is frequently observed in cancers and has been linked to tumor progression, invasion, and meta...

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Bibliographic Details
Main Authors:	Wenxiao Ji, Xinguo Zhuang, Wen G. Jiang, Tracey A. Martin
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Oncology
Subjects:	claudin CLDN tight junction blood brain barrier metastasis
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1596460/full
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