Morphological changes of thymus in immature rats following inhalation exposure of toluene

The aim of this study was to determine characteristics histological structure of the thymus of rats following inhalation exposure to toluene concentrations of 500 mg/m3 for 2 months. The experiment us ed white laboratory rats with initial body weight of 40-50 g, the studied area of the cortex and m...

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Main Author: Voloshin V.N.
Format: Article
Language:English
Published: State Institution "Dnipro State Medical University" 2012-01-01
Series:Морфологія
Subjects:
Online Access:http://www.morphology.dp.ua/_pub/MORPHO-2012-06-01/12vvmivt.pdf
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author Voloshin V.N.
author_facet Voloshin V.N.
author_sort Voloshin V.N.
collection DOAJ
description The aim of this study was to determine characteristics histological structure of the thymus of rats following inhalation exposure to toluene concentrations of 500 mg/m3 for 2 months. The experiment us ed white laboratory rats with initial body weight of 40-50 g, the studied area of the cortex and medulla of the thymus and their relationship. We calculated quantitatively in lymphoid cell po pulations of the body at different times after termination of the action of the studied facto rs. It is established that the effect of inhalation of toluene causes accidental thymus involution phenomena. In the action of toluene in different parts of the thymus observed phenomena toxicity and compensatory-adaptive changes. Longer after pre-reduction of toluene reduces the differences between histologi cal performance of the experimental and control groups.
format Article
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institution Matheson Library
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publishDate 2012-01-01
publisher State Institution "Dnipro State Medical University"
record_format Article
series Морфологія
spelling doaj-art-f3dda3b10f6a4f14b05e85b9c3a072892025-08-02T23:24:41ZengState Institution "Dnipro State Medical University"Морфологія1997-96652012-01-01612530Morphological changes of thymus in immature rats following inhalation exposure of tolueneVoloshin V.N.The aim of this study was to determine characteristics histological structure of the thymus of rats following inhalation exposure to toluene concentrations of 500 mg/m3 for 2 months. The experiment us ed white laboratory rats with initial body weight of 40-50 g, the studied area of the cortex and medulla of the thymus and their relationship. We calculated quantitatively in lymphoid cell po pulations of the body at different times after termination of the action of the studied facto rs. It is established that the effect of inhalation of toluene causes accidental thymus involution phenomena. In the action of toluene in different parts of the thymus observed phenomena toxicity and compensatory-adaptive changes. Longer after pre-reduction of toluene reduces the differences between histologi cal performance of the experimental and control groups.http://www.morphology.dp.ua/_pub/MORPHO-2012-06-01/12vvmivt.pdfthymusrathistologytoluene
spellingShingle Voloshin V.N.
Morphological changes of thymus in immature rats following inhalation exposure of toluene
Морфологія
thymus
rat
histology
toluene
title Morphological changes of thymus in immature rats following inhalation exposure of toluene
title_full Morphological changes of thymus in immature rats following inhalation exposure of toluene
title_fullStr Morphological changes of thymus in immature rats following inhalation exposure of toluene
title_full_unstemmed Morphological changes of thymus in immature rats following inhalation exposure of toluene
title_short Morphological changes of thymus in immature rats following inhalation exposure of toluene
title_sort morphological changes of thymus in immature rats following inhalation exposure of toluene
topic thymus
rat
histology
toluene
url http://www.morphology.dp.ua/_pub/MORPHO-2012-06-01/12vvmivt.pdf
work_keys_str_mv AT voloshinvn morphologicalchangesofthymusinimmatureratsfollowinginhalationexposureoftoluene