Evaluating Triazole-Substituted Pyrrolopyrimidines as CSF1R Inhibitors

6-Aryl-7<i>H</i>-pyrrolo[2,3-<i>d</i>]pyrimidin-4-amines have promising properties as colony-stimulating factor 1 receptor (CSF1R) inhibitors. Inspired by these antagonists, two series of 1,2,3-triazole analogues (28 compounds) were synthesized and evaluated as CSF1R inhibito...

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Bibliographic Details
Main Authors: Srinivasulu Cherukupalli, Jan Eickhoff, Carsten Degenhart, Peter Habenberger, Anke Unger, Bård Helge Hoff, Eirik Sundby
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/30/12/2641
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