Evaluating Triazole-Substituted Pyrrolopyrimidines as CSF1R Inhibitors
6-Aryl-7<i>H</i>-pyrrolo[2,3-<i>d</i>]pyrimidin-4-amines have promising properties as colony-stimulating factor 1 receptor (CSF1R) inhibitors. Inspired by these antagonists, two series of 1,2,3-triazole analogues (28 compounds) were synthesized and evaluated as CSF1R inhibito...
Saved in:
Main Authors: | Srinivasulu Cherukupalli, Jan Eickhoff, Carsten Degenhart, Peter Habenberger, Anke Unger, Bård Helge Hoff, Eirik Sundby |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2025-06-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/30/12/2641 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Design and Synthesis of Pyridine-Based Pyrrolo[2,3-<i>d</i>]pyrimidine Analogs as CSF1R Inhibitors: Molecular Hybridization and Scaffold Hopping Approach
by: Srinivasulu Cherukupalli, et al.
Published: (2025-05-01) -
In-vitro cytotoxic activities of poly(2-ethyl-2-oxazoline)-based amphiphilic block copolymers prepared by CuAAC click chemistry
by: S. Gulyuz, et al.
Published: (2018-02-01) -
Synthesis and Biological Evaluation of Some Coumarin–Triazole Conjugates as Potential Anticancer Agents
by: Anarkul S. Kishkentayeva, et al.
Published: (2025-03-01) -
Recent achievements in the synthesis and reactivity of pentafluorosulfanyl-alkynes
by: René, Floriane, et al.
Published: (2024-11-01) -
Bacteriological study of the cerebrospinal fluid(CSF) of children with meningitis in Baghdad
by: Ahmed .K.H.Al Hassan, et al.
Published: (2023-01-01)