Evidence-based principles of early diagnostics of carbohydrate metabolism disturbances in the internal disease practice
This review presents the World Health Organization (WHO) data on diabetes mellitus (DM) epidemiology, medical and social consequences, and economic losses due to DM complications. It is demonstrated that the diagnostics of early carbohydrate metabolism disturbances (ECMD) is an important component o...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2012-10-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1925 |
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| author | E. A. Poddubskaya M. N. Mamedov |
| author_facet | E. A. Poddubskaya M. N. Mamedov |
| author_sort | E. A. Poddubskaya |
| collection | DOAJ |
| description | This review presents the World Health Organization (WHO) data on diabetes mellitus (DM) epidemiology, medical and social consequences, and economic losses due to DM complications. It is demonstrated that the diagnostics of early carbohydrate metabolism disturbances (ECMD) is an important component of Type 2 DM (DM-2) prevention. At the same time, it is known that ECMD are an independent risk factor of cardiovascular disease (CVD). At early stages of DM-2, metabolic disturbances precede first clinical manifestations of diabetes. The importance of early (preclinical) diagnostics of ECMD is emphasised. The authors present the results of meta-analyses and large studies on DM and prediabetes, which have clearly demonstrated that pathological hyperglycemia cannot be diagnosed based only on fasting glucose levels, as this would underestimate the actual prevalence of prediabetes. Relevant methods of early ECMD diagnostics are described. |
| format | Article |
| id | doaj-art-f306d8ee9c624c0f910a0aa1f74df9c8 |
| institution | Matheson Library |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2012-10-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-f306d8ee9c624c0f910a0aa1f74df9c82025-08-04T12:50:17Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252012-10-01115838910.15829/1728-8800-2012-5-83-891639Evidence-based principles of early diagnostics of carbohydrate metabolism disturbances in the internal disease practiceE. A. Poddubskaya0M. N. Mamedov1State Research Centre for Preventive Medicine; I. M. Sechenov First Moscow State Medical University, MoscowState Research Centre for Preventive MedicineThis review presents the World Health Organization (WHO) data on diabetes mellitus (DM) epidemiology, medical and social consequences, and economic losses due to DM complications. It is demonstrated that the diagnostics of early carbohydrate metabolism disturbances (ECMD) is an important component of Type 2 DM (DM-2) prevention. At the same time, it is known that ECMD are an independent risk factor of cardiovascular disease (CVD). At early stages of DM-2, metabolic disturbances precede first clinical manifestations of diabetes. The importance of early (preclinical) diagnostics of ECMD is emphasised. The authors present the results of meta-analyses and large studies on DM and prediabetes, which have clearly demonstrated that pathological hyperglycemia cannot be diagnosed based only on fasting glucose levels, as this would underestimate the actual prevalence of prediabetes. Relevant methods of early ECMD diagnostics are described.https://cardiovascular.elpub.ru/jour/article/view/1925early disturbances of carbohydrate metabolismcardiovascular diseasediabetes mellitus |
| spellingShingle | E. A. Poddubskaya M. N. Mamedov Evidence-based principles of early diagnostics of carbohydrate metabolism disturbances in the internal disease practice Кардиоваскулярная терапия и профилактика early disturbances of carbohydrate metabolism cardiovascular disease diabetes mellitus |
| title | Evidence-based principles of early diagnostics of carbohydrate metabolism disturbances in the internal disease practice |
| title_full | Evidence-based principles of early diagnostics of carbohydrate metabolism disturbances in the internal disease practice |
| title_fullStr | Evidence-based principles of early diagnostics of carbohydrate metabolism disturbances in the internal disease practice |
| title_full_unstemmed | Evidence-based principles of early diagnostics of carbohydrate metabolism disturbances in the internal disease practice |
| title_short | Evidence-based principles of early diagnostics of carbohydrate metabolism disturbances in the internal disease practice |
| title_sort | evidence based principles of early diagnostics of carbohydrate metabolism disturbances in the internal disease practice |
| topic | early disturbances of carbohydrate metabolism cardiovascular disease diabetes mellitus |
| url | https://cardiovascular.elpub.ru/jour/article/view/1925 |
| work_keys_str_mv | AT eapoddubskaya evidencebasedprinciplesofearlydiagnosticsofcarbohydratemetabolismdisturbancesintheinternaldiseasepractice AT mnmamedov evidencebasedprinciplesofearlydiagnosticsofcarbohydratemetabolismdisturbancesintheinternaldiseasepractice |