H3K4me2 marks the enhancer: Enhancer logic in the zebrafish embryo.

At a key point in development, the embryo activates its genome: a shift that is largely coordinated by maternally derived factors. A new study in PLOS Biology identifies H3K4me2-marked enhancers in zebrafish that function independently and mirror the gamete state.

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Main Authors: Noura Maziak, Juan M Vaquerizas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-07-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3003257
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author Noura Maziak
Juan M Vaquerizas
author_facet Noura Maziak
Juan M Vaquerizas
author_sort Noura Maziak
collection DOAJ
description At a key point in development, the embryo activates its genome: a shift that is largely coordinated by maternally derived factors. A new study in PLOS Biology identifies H3K4me2-marked enhancers in zebrafish that function independently and mirror the gamete state.
format Article
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institution Matheson Library
issn 1544-9173
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language English
publishDate 2025-07-01
publisher Public Library of Science (PLoS)
record_format Article
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spelling doaj-art-f2f39b39daf24475b46c1b8e1373c7bb2025-07-16T05:30:51ZengPublic Library of Science (PLoS)PLoS Biology1544-91731545-78852025-07-01237e300325710.1371/journal.pbio.3003257H3K4me2 marks the enhancer: Enhancer logic in the zebrafish embryo.Noura MaziakJuan M VaquerizasAt a key point in development, the embryo activates its genome: a shift that is largely coordinated by maternally derived factors. A new study in PLOS Biology identifies H3K4me2-marked enhancers in zebrafish that function independently and mirror the gamete state.https://doi.org/10.1371/journal.pbio.3003257
spellingShingle Noura Maziak
Juan M Vaquerizas
H3K4me2 marks the enhancer: Enhancer logic in the zebrafish embryo.
PLoS Biology
title H3K4me2 marks the enhancer: Enhancer logic in the zebrafish embryo.
title_full H3K4me2 marks the enhancer: Enhancer logic in the zebrafish embryo.
title_fullStr H3K4me2 marks the enhancer: Enhancer logic in the zebrafish embryo.
title_full_unstemmed H3K4me2 marks the enhancer: Enhancer logic in the zebrafish embryo.
title_short H3K4me2 marks the enhancer: Enhancer logic in the zebrafish embryo.
title_sort h3k4me2 marks the enhancer enhancer logic in the zebrafish embryo
url https://doi.org/10.1371/journal.pbio.3003257
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AT juanmvaquerizas h3k4me2markstheenhancerenhancerlogicinthezebrafishembryo