Role of epicardial adipose tissue in the development of cardiovascular diseases
Epicardial adipose tissue (EAT) has unique properties due to its special anatomical structure, thermoregulation, and metabolic activity. Dysregulated EAT provokes the synthesis of pro-inflammatory cytokines, disorders in the metabolism of fats and glucose, as well as contributes to fatty degeneratio...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2022-03-01
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| Series: | Российский кардиологический журнал |
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| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/4872 |
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| author | I. A. Mustafina V. A. Ionin A. A. Dolganov V. Sh. Ishmetov A. E. Pushkareva T. A. Yagudin K. V. Danilko N Sh. Zagidullin |
| author_facet | I. A. Mustafina V. A. Ionin A. A. Dolganov V. Sh. Ishmetov A. E. Pushkareva T. A. Yagudin K. V. Danilko N Sh. Zagidullin |
| author_sort | I. A. Mustafina |
| collection | DOAJ |
| description | Epicardial adipose tissue (EAT) has unique properties due to its special anatomical structure, thermoregulation, and metabolic activity. Dysregulated EAT provokes the synthesis of pro-inflammatory cytokines, disorders in the metabolism of fats and glucose, as well as contributes to fatty degeneration of the myocardium and heart failure development. EAT may serve as a risk factor and biomarker for cardiovascular diseases, and is also a potential therapeutic target. The purpose of this review was to highlight current research data on EAT, secreted adipokines, their effect on target tissue metabolism, and to systematize the relationship between EAT and cardiovascular diseases. In particular, its function, role in heart failure, atrial fibrillation, as well as the prognostic value of various microRNAs determined in EAT are highlighted. |
| format | Article |
| id | doaj-art-f2cb3c238b1d478c89c8b4d3dc8f34b1 |
| institution | Matheson Library |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| publishDate | 2022-03-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj-art-f2cb3c238b1d478c89c8b4d3dc8f34b12025-08-04T13:00:27Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202022-03-01271S10.15829/1560-4071-2022-48723514Role of epicardial adipose tissue in the development of cardiovascular diseasesI. A. Mustafina0V. A. Ionin1A. A. Dolganov2V. Sh. Ishmetov3A. E. Pushkareva4T. A. Yagudin5K. V. Danilko6N Sh. Zagidullin7Bashkir State Medical UniversityPavlov First Saint Petersburg State Medical UniversityBashkir State Medical UniversityBashkir State Medical UniversityBashkir State Medical UniversityBashkir State Medical UniversityBashkir State Medical UniversityBashkir State Medical UniversityEpicardial adipose tissue (EAT) has unique properties due to its special anatomical structure, thermoregulation, and metabolic activity. Dysregulated EAT provokes the synthesis of pro-inflammatory cytokines, disorders in the metabolism of fats and glucose, as well as contributes to fatty degeneration of the myocardium and heart failure development. EAT may serve as a risk factor and biomarker for cardiovascular diseases, and is also a potential therapeutic target. The purpose of this review was to highlight current research data on EAT, secreted adipokines, their effect on target tissue metabolism, and to systematize the relationship between EAT and cardiovascular diseases. In particular, its function, role in heart failure, atrial fibrillation, as well as the prognostic value of various microRNAs determined in EAT are highlighted.https://russjcardiol.elpub.ru/jour/article/view/4872epicardial adipose tissuecardiovascular riskadipokinesmicrorna |
| spellingShingle | I. A. Mustafina V. A. Ionin A. A. Dolganov V. Sh. Ishmetov A. E. Pushkareva T. A. Yagudin K. V. Danilko N Sh. Zagidullin Role of epicardial adipose tissue in the development of cardiovascular diseases Российский кардиологический журнал epicardial adipose tissue cardiovascular risk adipokines microrna |
| title | Role of epicardial adipose tissue in the development of cardiovascular diseases |
| title_full | Role of epicardial adipose tissue in the development of cardiovascular diseases |
| title_fullStr | Role of epicardial adipose tissue in the development of cardiovascular diseases |
| title_full_unstemmed | Role of epicardial adipose tissue in the development of cardiovascular diseases |
| title_short | Role of epicardial adipose tissue in the development of cardiovascular diseases |
| title_sort | role of epicardial adipose tissue in the development of cardiovascular diseases |
| topic | epicardial adipose tissue cardiovascular risk adipokines microrna |
| url | https://russjcardiol.elpub.ru/jour/article/view/4872 |
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