Risk Measurement of TAVR Surgical Complications Based on Unbalanced Multilabel Classification Approaches

Transcatheter aortic valve replacement (TAVR) is a high-risk cardiovascular interventional procedure with a high incidence of postoperative complications, urgently requiring more refined risk identification and mitigation strategies. The main challenges in assessing the risk of TAVR complications li...

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Main Authors: Yue Zhang, Yuantao Xie
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Mathematics
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Online Access:https://www.mdpi.com/2227-7390/13/13/2139
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author Yue Zhang
Yuantao Xie
author_facet Yue Zhang
Yuantao Xie
author_sort Yue Zhang
collection DOAJ
description Transcatheter aortic valve replacement (TAVR) is a high-risk cardiovascular interventional procedure with a high incidence of postoperative complications, urgently requiring more refined risk identification and mitigation strategies. The main challenges in assessing the risk of TAVR complications lie in the scarcity of real-world data and the co-occurrence of multiple complications. This study developed an adjustment evaluation model that adapts randomised clinical trial (RCT) evidence to real-world data (RWD) and adopted multi-label classification methods that incorporate a LocalGLMnet-like regularization term, enabling data-adaptive parameter shrinkage for more accurate estimation. In the empirical analysis, with real surgical data from a hospital in the United States, a combination of multi-label random sampling and representative multi-label classification algorithms was used to fit the data. The model was compared across multiple evaluation metrics, including Hamming loss, ranking loss, and micro-AUC, to ensure robust results. The model used in this paper bridges the gap between medical risk prediction and insurance actuarial science, provides a practical data modelling foundation and algorithmic support for the future development of post-operative complication insurance products that precisely align with clinical risk.
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spelling doaj-art-f253d0f3ca8a4e19b74c48b5cf6572412025-07-11T14:40:35ZengMDPI AGMathematics2227-73902025-06-011313213910.3390/math13132139Risk Measurement of TAVR Surgical Complications Based on Unbalanced Multilabel Classification ApproachesYue Zhang0Yuantao Xie1School of Insurance, University of International Business and Economics, No. 10 Huixin East Street, Chaoyang District, Beijing 100029, ChinaSchool of Insurance, University of International Business and Economics, No. 10 Huixin East Street, Chaoyang District, Beijing 100029, ChinaTranscatheter aortic valve replacement (TAVR) is a high-risk cardiovascular interventional procedure with a high incidence of postoperative complications, urgently requiring more refined risk identification and mitigation strategies. The main challenges in assessing the risk of TAVR complications lie in the scarcity of real-world data and the co-occurrence of multiple complications. This study developed an adjustment evaluation model that adapts randomised clinical trial (RCT) evidence to real-world data (RWD) and adopted multi-label classification methods that incorporate a LocalGLMnet-like regularization term, enabling data-adaptive parameter shrinkage for more accurate estimation. In the empirical analysis, with real surgical data from a hospital in the United States, a combination of multi-label random sampling and representative multi-label classification algorithms was used to fit the data. The model was compared across multiple evaluation metrics, including Hamming loss, ranking loss, and micro-AUC, to ensure robust results. The model used in this paper bridges the gap between medical risk prediction and insurance actuarial science, provides a practical data modelling foundation and algorithmic support for the future development of post-operative complication insurance products that precisely align with clinical risk.https://www.mdpi.com/2227-7390/13/13/2139TAVR surgery complicationsimbalanced datamulti-label classification
spellingShingle Yue Zhang
Yuantao Xie
Risk Measurement of TAVR Surgical Complications Based on Unbalanced Multilabel Classification Approaches
Mathematics
TAVR surgery complications
imbalanced data
multi-label classification
title Risk Measurement of TAVR Surgical Complications Based on Unbalanced Multilabel Classification Approaches
title_full Risk Measurement of TAVR Surgical Complications Based on Unbalanced Multilabel Classification Approaches
title_fullStr Risk Measurement of TAVR Surgical Complications Based on Unbalanced Multilabel Classification Approaches
title_full_unstemmed Risk Measurement of TAVR Surgical Complications Based on Unbalanced Multilabel Classification Approaches
title_short Risk Measurement of TAVR Surgical Complications Based on Unbalanced Multilabel Classification Approaches
title_sort risk measurement of tavr surgical complications based on unbalanced multilabel classification approaches
topic TAVR surgery complications
imbalanced data
multi-label classification
url https://www.mdpi.com/2227-7390/13/13/2139
work_keys_str_mv AT yuezhang riskmeasurementoftavrsurgicalcomplicationsbasedonunbalancedmultilabelclassificationapproaches
AT yuantaoxie riskmeasurementoftavrsurgicalcomplicationsbasedonunbalancedmultilabelclassificationapproaches