Enhanced Cleaning, Enhanced Healing: A Systematic Review of Advances in Endodontic Irrigation

Background: Effective irrigation is crucial for successful endodontic treatment, ensuring debris removal, disinfection, and biofilm elimination. This systematic review analyzes recent advances in endodontic irrigants and activation systems. Materials and Methods: A comprehensive search of PubMed, Sc...

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Bibliographic Details
Main Authors: Shubhi Gupta, Karunakaran Venkataraman Jeyaraman, M. Deepthi, Rohan Shinkre, Neha Singh, Sagar Shah
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-06-01
Series:Journal of Pharmacy and Bioallied Sciences
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Online Access:https://journals.lww.com/10.4103/jpbs.jpbs_573_25
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Summary:Background: Effective irrigation is crucial for successful endodontic treatment, ensuring debris removal, disinfection, and biofilm elimination. This systematic review analyzes recent advances in endodontic irrigants and activation systems. Materials and Methods: A comprehensive search of PubMed, Scopus, Web of Science, and Google Scholar was conducted to identify relevant studies published between 2015 and 2025. Results: Emerging irrigants, including nanoparticle-based solutions, herbal formulations, and photoactivated disinfectants, demonstrate promising antimicrobial and biocompatibility properties. Advanced irrigation activation techniques, such as ultrasonic, laser-activated, and multisonic irrigation, enhance root canal debridement efficacy. Conclusions: This review highlights the strengths and limitations of recent advancements in endodontic irrigation, providing insights into their clinical implications and future research directions.
ISSN:0976-4879
0975-7406