Improvement of medication adherence in osteoporosis through telemedicine combined with email: a patient-reported experience and outcome measure-based prospective study
Objectives To evaluate whether adherence to oral bisphosphonate in patients with osteoporosis may be improved by teleconsultation (TC) with or without combined use of email to contact the bone specialist on-demand (enhanced TC).Methods 103 naïve patients with osteoporosis were prescribed branded ale...
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BMJ Publishing Group
2025-07-01
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| Series: | BMJ Health & Care Informatics |
| Online Access: | https://informatics.bmj.com/content/32/1/e101338.full |
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| author | Benedetta Pongiglione Amelia Compagni Gherardo Mazziotti Flaminia Carrone Michela Meregaglia Alessandra Angelucci Maria Laura Costantino Andrea Aliverti Andrea Gerardo Antonio Lania |
| author_facet | Benedetta Pongiglione Amelia Compagni Gherardo Mazziotti Flaminia Carrone Michela Meregaglia Alessandra Angelucci Maria Laura Costantino Andrea Aliverti Andrea Gerardo Antonio Lania |
| author_sort | Benedetta Pongiglione |
| collection | DOAJ |
| description | Objectives To evaluate whether adherence to oral bisphosphonate in patients with osteoporosis may be improved by teleconsultation (TC) with or without combined use of email to contact the bone specialist on-demand (enhanced TC).Methods 103 naïve patients with osteoporosis were prescribed branded alendronate (70 mg weekly) and randomised to three service modalities (presence, TC and enhanced TC), and evaluated for medication adherence after 12 months of follow-up. Patients allocated to the enhanced TC were provided with the opportunity to contact the bone specialists by email without any restriction. Patient-reported outcome(PROMs) and experience measures (PREMs) were evaluated with respect to the service modality.Results Of 89 patients who were persistent to therapy, 66% displayed optimal medication adherence, with odds being 4.5 higher in patients receiving enhanced TC versus those receiving the other services. TC service modality was considered in general to be worse in quality than in presence visits, whereas the combination with email use as in enhanced TC was sufficient to compensate for the perceived decrease in quality of care. Enhanced TC did not have any impact on the perception of quality of life as assessed by PROMs.Discussion In patients with osteoporosis, TC did not provide any advantage over traditional in presence visits in terms of improvement of adherence to therapy. However, when TC was combined with email to contact the bone specialist on demand, there was a significant improvement in adherence to the prescribed drug.Conclusions Patients with osteoporosis need to be supported after drug prescription to guarantee optimal medication therapy. |
| format | Article |
| id | doaj-art-f23a03082f9e49e5b29d4973b522e1cf |
| institution | Matheson Library |
| issn | 2632-1009 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | BMJ Publishing Group |
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| series | BMJ Health & Care Informatics |
| spelling | doaj-art-f23a03082f9e49e5b29d4973b522e1cf2025-07-22T04:30:10ZengBMJ Publishing GroupBMJ Health & Care Informatics2632-10092025-07-0132110.1136/bmjhci-2024-101338Improvement of medication adherence in osteoporosis through telemedicine combined with email: a patient-reported experience and outcome measure-based prospective studyBenedetta Pongiglione0Amelia Compagni1Gherardo Mazziotti2Flaminia Carrone3Michela Meregaglia4Alessandra Angelucci5Maria Laura Costantino6Andrea Aliverti7Andrea Gerardo Antonio Lania83 Bocconi University, Centre for Research on Health and Social Care Management, Milano, ItalyDepartment of Social and Political Sciences, Bocconi University, Milano, ItalyDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele-Milan, ItalyEndocrinology, Diabetology and Andrology Unit, IRCCS Humanitas Research Hospital, Rozzano, ItalyCentre for Research in Health and Social Care Management (CeRGAS) sda, Bocconi University, Milano, ItalyDipartimento Di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milano, ItalyDepartment of Chemistry, Materials and Chemical Engineering Giulio Natta, Politecnico di Milano, Milano, ItalyDipartimento Di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milano, ItalyDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele-Milan, ItalyObjectives To evaluate whether adherence to oral bisphosphonate in patients with osteoporosis may be improved by teleconsultation (TC) with or without combined use of email to contact the bone specialist on-demand (enhanced TC).Methods 103 naïve patients with osteoporosis were prescribed branded alendronate (70 mg weekly) and randomised to three service modalities (presence, TC and enhanced TC), and evaluated for medication adherence after 12 months of follow-up. Patients allocated to the enhanced TC were provided with the opportunity to contact the bone specialists by email without any restriction. Patient-reported outcome(PROMs) and experience measures (PREMs) were evaluated with respect to the service modality.Results Of 89 patients who were persistent to therapy, 66% displayed optimal medication adherence, with odds being 4.5 higher in patients receiving enhanced TC versus those receiving the other services. TC service modality was considered in general to be worse in quality than in presence visits, whereas the combination with email use as in enhanced TC was sufficient to compensate for the perceived decrease in quality of care. Enhanced TC did not have any impact on the perception of quality of life as assessed by PROMs.Discussion In patients with osteoporosis, TC did not provide any advantage over traditional in presence visits in terms of improvement of adherence to therapy. However, when TC was combined with email to contact the bone specialist on demand, there was a significant improvement in adherence to the prescribed drug.Conclusions Patients with osteoporosis need to be supported after drug prescription to guarantee optimal medication therapy.https://informatics.bmj.com/content/32/1/e101338.full |
| spellingShingle | Benedetta Pongiglione Amelia Compagni Gherardo Mazziotti Flaminia Carrone Michela Meregaglia Alessandra Angelucci Maria Laura Costantino Andrea Aliverti Andrea Gerardo Antonio Lania Improvement of medication adherence in osteoporosis through telemedicine combined with email: a patient-reported experience and outcome measure-based prospective study BMJ Health & Care Informatics |
| title | Improvement of medication adherence in osteoporosis through telemedicine combined with email: a patient-reported experience and outcome measure-based prospective study |
| title_full | Improvement of medication adherence in osteoporosis through telemedicine combined with email: a patient-reported experience and outcome measure-based prospective study |
| title_fullStr | Improvement of medication adherence in osteoporosis through telemedicine combined with email: a patient-reported experience and outcome measure-based prospective study |
| title_full_unstemmed | Improvement of medication adherence in osteoporosis through telemedicine combined with email: a patient-reported experience and outcome measure-based prospective study |
| title_short | Improvement of medication adherence in osteoporosis through telemedicine combined with email: a patient-reported experience and outcome measure-based prospective study |
| title_sort | improvement of medication adherence in osteoporosis through telemedicine combined with email a patient reported experience and outcome measure based prospective study |
| url | https://informatics.bmj.com/content/32/1/e101338.full |
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