Virtual and experimental screening of new melatonin bioisosteres for the treatment of glaucoma

Background. Melatonin is an endogenous regulator of intraocular pressure (IOP), but its effectiveness as a drug for glaucoma treatment is limited.The  aim of  the  study. To develop and  to  validate a  virtual screening method to identify bioisosteric analogs of melatonin that are promising for stu...

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Main Authors: D. A. Babkov, A. S. Taran, A. A. Shevchenko, L. V. Naumenko, O. N. Zhukovskaya, A. M. Efremov, E. N. Bezsonova, N. A. Lozinskaya, A. A. Spasov
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2024-03-01
Series:Acta Biomedica Scientifica
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Online Access:https://www.actabiomedica.ru/jour/article/view/4606
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